Chapter 6. Agents Affecting Appetite

Heil, George C.; Ross, Stephen T.

doi:10.1016/s0065-7743(08)61234-8

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Introduction2

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1977

2018

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Cited by 4 publications

(2 citation statements)

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“…Холецистокинин (ХЦК) снижает аппетит как у людей, так и у животных. Были разработаны и протестированы аналоги пептида, но никаких клинических данных опубликовано не было [16].…”

Section: Introductionunclassified

Pharmacotherapy of Obesity: Past, Present and Future

Ткач¹,

Тимошенко²

2016

CE&ES

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Section: Introductionunclassified

Pharmacotherapy of Obesity: Past, Present and Future

Ткач¹,

Тимошенко²

2016

CE&ES

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“…Phenylalkylamine derivatives which have anorectic effects and yet produce few of the central stimulant effects which are characteristic of amphetamine can be produced by substitution on the amphetamine structure (Heil & ROSS, 1973). An examination of the anorectic and central stimulant effects of a range of closed-ring analogues of amphetamine may provide an approach to the design of non-stimulant anorectics.…”

Section: Introductionmentioning

confidence: 99%

Comparison of the Anorectic and Motor Activity Effects of Some Aminoindanes, 2‐aminotetralin and Amphetamine in the Rat

Mrongovius¹,

Bolt²,

Hellyer³

1978

Clin Exp Pharma Physio

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1. The anorectic and motor activity effects of 1-aminoindane, 2-aminoindane, some N-substituted 2-aminoindanes, 2-aminotetralin, amphetamine and fenfluramine were determined in rats. 2. The two compounds with structures most like the extended conformation of amphetamine, 2-aminotetralin and 2-aminoindane, were potent anorectics. At dosages which halved the intake of food over 1 h, amphetamine increased motor activity, 2-aminotetralin had no effect, and 2-aminoindane reduced motor activity. 3. Both the anorectic and central stimulant actions of 2-aminoindane were absent in N-ethyl- and N-isopropyl-2-aminoindane. 4. 1-Aminoindane, whose structure is like the folded conformation of amphetamine, produced a small anorectic effect and depressed motor activity.

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The Psychopharmacology of Feeding

Hoebel

1977

Drugs, Neurotransmitters, and Behavior

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Chapter 6. Agents Affecting Appetite

Cited by 4 publications

References 44 publications

Pharmacotherapy of Obesity: Past, Present and Future

Pharmacotherapy of Obesity: Past, Present and Future

Comparison of the Anorectic and Motor Activity Effects of Some Aminoindanes, 2‐aminotetralin and Amphetamine in the Rat

The Psychopharmacology of Feeding

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