1985
DOI: 10.1016/s0167-7306(08)60677-8
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Chapter 1 Biosynthesis of cholesterol

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Cited by 16 publications
(13 citation statements)
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“…3) in plants (Grunwald, 1975;Goodwin, 1985) and animals (Rilling and Chayet, 1985). The LKB gene may not be involved in this conversion because the lkb mutant and WT contained similar levels of cholesterol in their shoots, seeds, and microsomal membranes (Tables III and V).…”
Section: Br Deficiency In the Lkb Mutant Is Due To Impaired Synthesismentioning
confidence: 99%
“…3) in plants (Grunwald, 1975;Goodwin, 1985) and animals (Rilling and Chayet, 1985). The LKB gene may not be involved in this conversion because the lkb mutant and WT contained similar levels of cholesterol in their shoots, seeds, and microsomal membranes (Tables III and V).…”
Section: Br Deficiency In the Lkb Mutant Is Due To Impaired Synthesismentioning
confidence: 99%
“…A possible candidate to be modified by prenylation is the viral protein encoded by the open reading frame L83L, which contains a carboxyl-terminal CTIL type I geranylgeranylation motif (35) and is transcribed at a late time of infection. 2 The use of drugs known to interfere with the prenylation of proteins may also help to understand the role, if any, of protein prenylation during the infectious cycle.…”
Section: Table Imentioning
confidence: 99%
“…Attempts to construct ASFV recombinants depleted of the trans-prenyltransferase gene have failed, 2 suggesting that the gene is essential for virus multiplication. A system for inducible gene expression from ASFV recombinants, recently developed in our laboratory (36), might be useful to investigate the role of the trans-prenyltransferase during virus replication.…”
Section: Table Imentioning
confidence: 99%
“…Steroidal demethylation at C-14 in yeast, rat, and plants is known to proceed via C-14 hydroxymethyl and C-14 aldehyde (Goodwin 1985, Rilling andChayet 1985). The removal of two sterol C-4 methyl groups proceeds stepwise oxidation of the methyl group to a carboxyl group (Goodwin 1985, Rilling andChayet 1985).…”
mentioning
confidence: 99%
“…The removal of two sterol C-4 methyl groups proceeds stepwise oxidation of the methyl group to a carboxyl group (Goodwin 1985, Rilling andChayet 1985). Thus, C-26 demethylation of BRs is expected to be formed via intermediates with C-26 being a hydroxymethyl, aldehyde or carboxyl group.…”
mentioning
confidence: 99%