Chaparral Induced Renal Failure

Abstract

We report a patient presenting with adverse effects of an herbal supplement, Chaparral, which has been marketed to treat colds, skin disorders, arthritis, bladder infections, and even cancer, among other conditions. It is not approved by the FDA and there has been no research to support its marketed benefits. Some of the reported adverse effects include liver and kidney failure. Our patient presented with uremia. She was ruled out for other causes of renal failure such as glomerular disease, viral causes, and obstruction. Bilateral kidney ultrasound showed atrophic kidneys suggestive of acute on chronic kidney failure. This was successfully treated with hemodialysis during her hospitalization and was discharged with need for long term dialysis and follow up for potential renal transplant. This case illustrates the severe adverse effects that can occur as a result of Chaparral use in a patient using this medicine and reinforces the importance of a thorough medication history.