“…Given that such flows evolving near the edge of regularity involve the formation of very small flow structures, these computations typically require the use of state-of-the-art computational resources available at a given time. The computational studies focused on the possibility of finite-time blow-up in the 3-D Navier-Stokes and/or Euler system include Brachet et al (1983), Pumir & Siggia (1990), Brachet (1991), Kerr (1993), Pelz (2001), , Ohkitani & Constantin (2008), Ohkitani (2008), Grafke et al (2008), Gibbon et al (2008), Hou (2009), Orlandi, Pirozzoli & Carnevale (2012), Bustamante & Brachet (2012), Orlandi et al (2014) and Campolina & Mailybaev (2018), all of which considered problems defined on domains periodic in all three dimensions. The investigations by Donzis et al (2013), Kerr (2013b) and Gibbon et al (2014) and Kerr (2013a) focused on the time evolution of vorticity moments and compared it against bounds on these quantities obtained using rigorous analysis.…”