Chaotic approach in biomedicine: Individualized medical treatment

Abstract

<span style="font-family:Verdana;font-size:10pt;">According to classic deterministic-stochastic approaches, we don’t have any possibility for realization of the basic principle in medicine because every human organism has its own specific features. It is evident for us that requirement of medical personification includes two procedures: individual (with uninterrupted procedure of human organism state measurement) diagnostics and the second part which is connected with uninterrupted control of the efficiency of medical treatment and measurements of human organism parameters. We conduct the diagnostics according to behavior of state vector of human organism in phase space of states according to every coordinates of human’s state vector and with calculation of quasiattractors. We can present the results of our observations: what may be good for one person is not necessarily good for another. We present new bioinformational methods and software for calculation of quasiattractors parameters for dissolving such contradictions between deterministic-stochastic medicine and the use of theory of chaos self-organization where the state vector of human organism demonstrates uninterrupted movements. The practical results of such procedure are also presented according to the theory of chaos-self-organization. So there are great distinctions between the classic deterministic-stochastic approach (based on traditional medicine requirements) and the new theory of chaos self-organization which considers every human organism as a unique system with individual properties.</span

Recurrence-specific supervised graph clustering for subtyping Hodgkin Lymphoma radiomic phenotypes

“…having lower risk of recurrence, exhibit statistically relevant lower lesions' dispersion, lower lesions' volume, more spherical lesions, and higher entropy within lesions with respect to patients belonging to risk class 2, who instead express higher dispersion and volume, lower entropy and more irregular lesions' shapes. As dispersion is intended as a proxy of intra-tumor heterogeneity, we notice how higher heterogeneous diseases are associated to poorer clinical outcomes, while lesion-specific entropy values are linked to more positive responses, as shown in other medical applications [23]. The employment of patient-wise lesions' dispersion as intra-tumor heterogeneity proxy paves the way towards the assessment of tumor evolution in a personalized medicine fashion, beyond standard prognosis recommendations.…”

Prediction of Khanty People Life Expectancy According to Chaotic Dynamics of Their Cardiovascular System Parameters

“…В этом случае необходимо наблюдать ВСС за некоторый период времени T и определять области в ФПС, в пределах которых ВСС движется в ФПС [14]. Эти области мы определяем как КА, а их параметры имеют информационное значение (их объем V G и координаты их центра, а также положение этих КА для группы обследуемых по отношению к другой группе обследуемых) [15,16].…”

An analysis of I.R. Prigogone and J.A. Wheeler’s views concerning emergency of biosystems from the perspective of the third paradigm

“…Для эмерджентных систем, СТТ-complexity, прошлое и настоящее не может существенно влиять на будущее, которое не прогнозируется на основе знаний x(t 0 ) и это очень похоже на хаос в ДСН. Однако, детерминированный хаос имеет другие свойства, чем СТТ [14,15] [6]. Нет смысла говорить о создании новых теорий для детерминистских или стохастичных систем (1-го и 2-го типа по W. Weaver).…”