Changing trends in the prevalence of coronary heart disease

Sriharibabu, M

doi:10.1016/j.ihj.2016.04.008

Cited by 9 publications

(8 citation statements)

References 1 publication

(1 reference statement)

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“…Hseuh et al [1] in a study included 113 patients of whom 68 (60.2%) were males and 45 (39.8%) females. In another study, prevalence of CAD was 6.5 times higher in males than females [8]. Transient AV block is a common complication of acute MI [especially inferior wall myocardial infarction (IWMI)].…”

Section: Discussionmentioning

confidence: 98%

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Prevalence of Coronary Artery Disease and Its Risk Factors in Patients Undergoing Permanent Pacemaker Implantation

Jayaram

Iype

Karkera

et al. 2019

ijcp

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Introduction: Some pacemaker implanted patients have an atherosclerotic disease which promotes conduction system ischemia and conduction disturbances. The aim of this study was to determine prevalence of coronary artery disease (CAD) and its risk factors in patients undergoing permanent pacemaker implantation (PPI). Methods: This prospective, single-center hospital based study examined patients older than 40 years who required PPI. Presence of atherosclerotic risk factors and CAD was examined. Results: Of 258 patients undergoing PPI, CAD was present in 50 (19.37 %) patients. CAD was more common among middle age and elderly patients (P = 0.03). Patients older than or equal 76.5 years had specificity of 78.8% for an association with CAD. Multivariate analysis showed that age (odds ratio: 1.042; 95% confidence interval: 1.009-1.075; P = 0.01) and diabetes (odds ratio: 3.437; 95% confidence interval: 1.618-7.303; P = 0.001) had a statistically significant association with CAD. Of 169 patients with involvement of the atrioventricular (AV) node, 28 (16.6 %) had associated left anterior descending artery (LAD) involvement with P = 0.01, suggesting an association between LAD disease and chronic degenerative changes in the AV node. Conclusion: CAD was present in 19.4% of patients undergoing PPI. Age and diabetes had a strong association with CAD. LAD stenosis was significantly more prevalent in AV nodal/ infra-hisian disease compared with sinus nodal disease.

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Section: Discussionmentioning

confidence: 98%

“…During 1960 CAD prevalence rates were based on autopsy reports and insurance statistics. According to these studies, prevalence rates varied between 0.49-0.63% [8]. Hseuh et al [1] performed selective CAG on 113 patients with symptomatic bradyarrhythmia and found incident CAD in 20% of these patients.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Coronary Artery Disease and Its Risk Factors in Patients Undergoing Permanent Pacemaker Implantation

Jayaram

Iype

Karkera

et al. 2019

ijcp

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“…We believe that these findings may help in decision-making of management strategy in young patients with CAD. According to the National Commission on Macroeconomics and health estimate, patients with CAD in India have increased from 29.8 to 61.5 million from 2004 to 2015 and the mortality rate has increased from 1.3 to 2.946 million [16]. Numerous studies have shown that high levels of LDL cholesterol are directly related to coronary artery disease [17,18] and low level of HDL cholesterol has been considered as one of the strongest and most independent risk factors for the coronary artery disease [19,20].…”

Section: Discussionmentioning

confidence: 99%

Lipid Profile Parameters and Coronary Artery Disease in Young Patients Undergoing Diagnostic Angiography

Jayaram

Nayak

Rao

et al. 2019

ijcp

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Introduction: It is vital to understand the association between lipid profile and the severity of coronary artery disease (CAD) in young patients with suspected CAD. The clinical presentation, lipid profile and severity of CAD may differ in patients who develop CAD at young age and those at older age. Friesinger (FR) index is an important tool to assess the extent and severity of coronary artery lesions. Methods: This study was a single center retrospective study involving patients below 40 years who underwent diagnostic coronary angiography. Demographic variables, lipid profile and FR index were estimated. Patients were divided into four groups based on the FR index scores of 0, 1-4, 5-10 and 11-15, respectively. Results: A total of 158 patients (Mean ± SD of age; 35.65 ± 3.81 years) were included in the study. Among demographic variables, gender (P = 0.03) and body mass index (BMI) (P < 0.001) were found to be associated with FR index. In addition, total cholesterol (P < 0.001), low density cholesterol (LDL) cholesterol (P < 0.001), nonhigh density cholesterol (non-HDL) (P < 0.001) and ratio of triglycerides (TG) /non-HDL cholesterol (P = 0.004) showed significant differences between the FR groups. Logistic regression analysis showed that only diabetes (P = 0.02) and BMI (P = 0.004) were significant predictors of the extent and severity of coronary artery lesions in terms of FR index. Conclusions: A strong direct relationship was observed between total cholesterol, LDL and non HDL cholesterol while a negative correlation with the TG/non HDL ratio. Diabetes and BMI also play a very significant role.

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“…2 Prevalence of CAD was 6.5 times higher in men compared with womem. 3 The first Indian study by Dewan et al involving Minnesota codes was done in 1974, which reported CAD prevalence of 2.28% in men and 1.73% in women in rural Maharashtra. 4 In 1991-1994, ICMR (Indian Council of Medical Research) task force study was conducted in which CAD prevalence rates were 11% and 10% in urban Delhi among men and women, respectively.…”

Section: Discussionmentioning

confidence: 99%

Changing Trends of Angiographic Profiles in Women with Coronary Artery Disease over a Decade

Aramalla¹,

Chakkera

2018

Ind J Car Dis Wom

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Background Cardiovascular diseases, especially coronary artery disease (CAD), have assumed epidemic proportions worldwide. CAD is the leading cause of disability and death in women. In woman during postmenopausal years, traditional risk factors tend to become very present and increase the risk for CAD. Patterns in epidemiology of CAD are doubtlessly changing continually in many ways, only some of which are recognized at any given point of time. Aim To identify the changing trends of CAD in female patients who were admitted for coronary angiogram (CAG) over a period of 10 years. Materials and Methods We retrospectively collected the data of female patients from our unit CAG registry. We noted the demographic data (age, ethnicity, socioeconomic status), clinical data (diabetic status, hypertension status, symptoms and their duration, past history), laboratory data (complete blood picture, cardiac enzymes, renal function tests, liver function tests, serum electrolytes), and CAG findings (normal coronaries [NC]/single-vessel disease [SCD]/double-vessel disease [DVD]/triple-vessel disease [TVD]) of the female patients in 2007 and a decade later that was 2017. Results Data of 64 women in 2007 and of 184 in 2017 were analyzed. CAG women in 2017 were older than those in 2007 (53.1 ± 11.7 vs. 57.1 ± 12.3 years; p = 0.024). There was no significant difference found in the parameters such as hypertension (p = 0.797), diabetes mellitus (DM) (37.5% vs. 41.3%; p = 0.59), left ventricular (LV) dysfunction, type of presentation (acute coronary syndrome [ACS] or chronic stable angina [CSA]) and presence of CAD (53.9% vs. 51.1%; p = 0.69). In the 2017 female group, there was increase in detection of the electrographic (ECG) abnormalities (98.4% vs. 62.5%; p = 0.000). Radial route was used more frequently for CAG (98.4% vs. 40.6%; p = 0.000). Subgroup analysis of CAD (proven angiographically) showed a statistically significant difference of occurrence of SVD that was more frequent in 2007 female group (32.8% vs. 20.1%; p = 0.05), whereas TVD (was more frequent in 2017 female group (14.1% vs. 4.6%; p = 0.01). Conclusion This study shows that even though there was no change in the incidence of occurrence of normal coronaries on angiogram over time; however, there was a significant increase in severity of the CAD (TVD) in 2017 female group (p = 0.01).

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Changing trends in the prevalence of coronary heart disease

Cited by 9 publications

References 1 publication

Prevalence of Coronary Artery Disease and Its Risk Factors in Patients Undergoing Permanent Pacemaker Implantation

Prevalence of Coronary Artery Disease and Its Risk Factors in Patients Undergoing Permanent Pacemaker Implantation

Lipid Profile Parameters and Coronary Artery Disease in Young Patients Undergoing Diagnostic Angiography

Changing Trends of Angiographic Profiles in Women with Coronary Artery Disease over a Decade

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