Changing the zinc:iron ratio in a cereal-based nutritional supplement has no effect on percent absorption of iron and zinc in Sri Lankan children

Hettiarachchi, Manjula; Liyanage, Chandrani; Hilmers, David C.; Griffin, Ian J.; Abrams, Steven A.

doi:10.1017/s0007114509992728

Cited by 12 publications

(11 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We observed that the mean consumption of iodine-containing nutrient supplements was not satisfactory (mean = 10.77 μg/day). In addition, the iodine level of nutrient supplements, including Soy flour and Thriposha, was approximately between 0.2–0.4 μg/g [ 70 ]. Gordon et al (1998) claimed that iodine supplementation (150 μg iodine/day for 28 weeks) increased the UIC in children who had mild ID (63 μg/L) [ 71 ].…”

Section: Discussionmentioning

confidence: 99%

Factors influencing the iodine status of children aged 12 to 59 months from Jaffna District, Sri Lanka in the post-iodization era; a descriptive, cross-sectional study

2021

View full text Add to dashboard Cite

Background Iodine status, including Iodine Deficiency (ID) of the children aged 12–59 months of Jaffna District, Sri Lanka, have never been studied. This study thus aimed to assess ID among children aged 12–59 months by monitoring the Urinary Iodine Concentrations (UIC), the prevalence of goitre, and the factors causing ID. Method A cross-sectional study was conducted among 846 children aged 12–59 months in Jaffna District, Sri Lanka. Sociodemographic characteristics and other factors were collected using an interviewer-administered questionnaire. Dietary pattern of children was obtained using semi-quantitative food frequency questionnaire. We performed urinary iodine estimation and physical examinations to detect the goitre, according to the World Health Organization criteria. A multivariate logistic linear regression model was used to identify the factors that causing ID. Result The median UIC was 146.4 μg/L (interquartile range = 112.6–185.3 μg/L). Based on the UIC (<100 μg/L), 17.8% had ID, of which 15.7% and 2.1% had mild and moderate ID. The mean consumption of iodine from food was 128.7 (±20.2) μg/day. Gender variation had no influence on ID (p>0.05). Median UIC was significantly associated with living area, wealth status, type of drinking water, and method of iodized salt usage. A higher percentage of ID was significantly associated with younger age [AOR 2.32 (95% CI: 1.31–4.10)], urban area [AOR 1.94 (95% CI 1.27–2.96)], inland regions [AOR 3.20 (95% CI 1.85–5.55)], improper method of iodized salt usage [AOR 3.63 (95% CI: 1.38–9.56)], and low consumption of iodine-containing foods. The neck palpation revealed that only three children had goitre (0.4%). Conclusion This study revealed that high ID among the children in Jaffna children was due to improper usage of iodized salt, even though the iodized salt is freely available in the region, living area, and age, while the prevalence of goitre was not significantly identified as a public health problem.

show abstract

Section: Discussionmentioning

confidence: 99%

Factors influencing the iodine status of children aged 12 to 59 months from Jaffna District, Sri Lanka in the post-iodization era; a descriptive, cross-sectional study

2021

View full text Add to dashboard Cite

show abstract

“…Haschke et al (1986) 56 No significant difference in absorption between fortified (iron, 10.2 mg/L) and unfortified product (iron, 2.5 mg/L) Szymlek-Gay et al (2016) 103 Neither supplemental iron (iron, 1. 128 No significant difference in zinc absorption between high (iron, 9 mg) and low (iron, 4.5 mg) supplementation. Phytate/phytase intake 0-3 years (n ¼ 3) Brni c et al (2017) 90 Adding 20.5 phytase units in meals (phytic acid content, 108.2 mg) can increase zinc absorption in young children.…”

Section: Reference Conclusionmentioning

confidence: 96%

“…Factors affecting zinc bioavailability. A total of 30 studies reported data on the efficacy of zinc absorption in children aged 0 to 9 years, 39,53,56,63,65,66,68,80,88,[90][91][92][94][95][96][97][98][99][100][103][104][105][123][124][125][126][127][128][129][130] of which 19 were conducted in the target age range of 0 to 3 years. 39,53,56,66,88,[90][91][92][94][95][96][97]99,100,[103][104][105]124,129 Results from these studies are summarized in Table 3.…”

Section: Data Synthesismentioning

confidence: 99%

“…These studies reported on the bioavailability of zinc in the presence of iron, 56,[95][96][97]103,125,128 calcium, 53,68 Na 2 EDTA (ethylenediaminetetraacetic acid disodium salt), 94,127 long-term exposure to zinc, 129 phytate/phytase, 63,80,90,104,105,124,130 dietary fiber, 92 resistant starch, 65 lactose, 88 or environmental enteric dysfunction 39,66 ; the bioavailability of zinc from fortified vs biofortified foods, 91,98 plant-vs animal-source foods with and without human milk, 99,126 human milk vs formula milk, 100 ; and the bioavailability of zinc in the presence or absence of a meal. 104,123 Overall, there were no statistically significant changes in the bioavailability of zinc in the presence of iron, 56,[95][96][97]103,125,128 lactose, 88 calcium, 53,68 resistant starch, 65 or dietary fiber. 92 Results from one study suggested that zinc absorption in formula-fed children was lower than that in children fed breast milk.…”

Section: Data Synthesismentioning

confidence: 99%

See 1 more Smart Citation

Toward revising dietary zinc recommendations for children aged 0 to 3 years: a systematic review and meta-analysis of zinc absorption, excretion, and requirements for growth

et al. 2022

View full text Add to dashboard Cite

Context The Food and Agriculture Organization of the United Nations and the World Health Organization are updating their dietary zinc recommendations for children aged 0 to 3 years. Objective The aim of this review was to retrieve and synthesize evidence regarding zinc needs for growth as well as zinc losses, absorption, and bioavailability from the diet. Data Sources MEDLINE, Embase, and Cochrane Library databases were searched electronically from inception to August 2020. Studies assessing the above factors in healthy children aged 0 to 9 years were included, with no limits on study design or language. Data Extraction Ninety-four studies reporting on zinc content in tissue (n = 27); zinc absorption (n = 47); factors affecting zinc bioavailability (n = 30); and endogenous zinc losses via urine, feces, or integument (n = 40) met the inclusion criteria. Four reviewers extracted data and two reviewers checked for accuracy. Data Analyses Studies were synthesized narratively, and meta-analyses of zinc losses and gains as well the subgroups of age, type of feeding, country’s income, and molar ratio of phytate to zinc were conducted. Meta-analysis revealed an overall mean (95%CI) urinary and endogenous fecal zinc excretion of 17.48 µg/kg/d (11.80–23.15; I2 = 94%) and 0.07 mg/kg/d (0.06–0.08; I2 = 82%), respectively, with a mean fractional zinc absorption of 26.75% (23.69–29.81; I2 = 99%). Subgrouping by age revealed differences in mean values associated with the transition from milk-based diets to solid food during the first 3 years of life. Conclusion This review synthesizes data that may be used to formulate zinc requirements in young children. Results should be interpreted with caution because of considerable heterogeneity in the evidence. Systematic Review Registration PROSPERO registration number CRD42020215236.

show abstract

“…Several human studies have reported on zinc-iron interactions in fortified water (10), wheat flour (7,11), and other cereals (12). The effect of zinc on iron bioavailability from fortified foods, liquids, and supplements has been reviewed (13).…”

Section: Introductionmentioning

confidence: 99%

Research on Natural Resources: The Quest for Integration Revisited

Bornemann¹,

Bernasconi²,

Ejderyan³

et al. 2017

GAIA - Ecological Perspectives for Science and Society

View full text Add to dashboard Cite

The dysfunctional use of resources in modern societies arises from increasingly fragmented ways of understanding natural resources. Consequently, there have been repeated calls for integrative knowledge production, and various approaches to integration have been proposed, including such as interdisciplinary or transdisciplinary resource research and integrated resource management. The conceptual space proposed here can be applied as a tool for imagining and designing new approaches, methods, and research techniques toward a more reflexive understanding of integration-oriented research on natural resources.

show abstract

Changing the zinc:iron ratio in a cereal-based nutritional supplement has no effect on percent absorption of iron and zinc in Sri Lankan children

Cited by 12 publications

References 30 publications

Factors influencing the iodine status of children aged 12 to 59 months from Jaffna District, Sri Lanka in the post-iodization era; a descriptive, cross-sectional study

Factors influencing the iodine status of children aged 12 to 59 months from Jaffna District, Sri Lanka in the post-iodization era; a descriptive, cross-sectional study

Toward revising dietary zinc recommendations for children aged 0 to 3 years: a systematic review and meta-analysis of zinc absorption, excretion, and requirements for growth

Research on Natural Resources: The Quest for Integration Revisited

Contact Info

Product

Resources

About