Changing the Nature of Melanoma Cells by Manipulation of Ganglioside Expression

Emerging GM3 Regulated Biomarkers in Malignant Melanoma

“…Moreover, we would elucidate the mechanism that GM3 regulate melanoma metastasis via the genes, such as Ly-GDI, TNF-α, MMP-9, MMP-2, Caveolin-1 and Plaur, etc. and the functions of these genes on the phenotypes of melanoma cells, such as invasive proliferation, adhesion, migration and invasion would be finally addressed based on our and others' publications (Table 1) [6].…”