Changing prevalence of Helicobacter pylori infection in children and adolescents

Park, Ji Sook; Jun, Jin Su; Seo, Ji‐Hyun; Youn, Hee Shang; Rhee, Kwang‐Ho

doi:10.3345/cep.2019.01543

Cited by 39 publications

(29 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…6 Even with suggestions of a possible link with growth retardation and iron deficiency anaemia in children, limited evidence has affected research efforts. 6,8 In a 2017 study, 9 a global prevalence of 33% was estimated for HPI in childhood, but without a breakdown by sub-regions, countries, and geographical settings which would be quite useful for preventive measures in specific settings. Moreover, no study has systematically reviewed the risk factors for HPI in children.…”

Section: Introductionmentioning

confidence: 99%

The global prevalence of and factors associated with Helicobacter pylori infection in children: a systematic review and meta-analysis

Yuan

Adeloye

Luk

et al. 2022

The Lancet Child & Adolescent Health

108

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 99%

The global prevalence of and factors associated with Helicobacter pylori infection in children: a systematic review and meta-analysis

Yuan

Adeloye

Luk

et al. 2022

The Lancet Child & Adolescent Health

108

View full text Add to dashboard Cite

“…Helicobacter pylori infection in adults is usually chronic and will not heal without specific therapy; on the other hand, spontaneous elimination of the bacterium in childhood is probably relatively common, aided by the administration of antibiotics for other reasons [32]. Based on this assertion, infection among the studied population here could have been due to childhood infection [1,5] and [7] that still persisted within the infected individuals.…”

Section: Discussionmentioning

confidence: 81%

“…In a recent review, Park et al [7] discussed a changing prevalence of Helicobacter pylori infection in children and adolescents. They concluded that age and sex are not significantly associated with H. pylori infection in children and adults.…”

Section: Introductionmentioning

confidence: 99%

Seroprevelance of Helicobacter pylori Infection among Students of Bingham University, Karu in North-Central Nigeria

Abioye

Anarado

Babatunde

2021

IJPR

View full text Add to dashboard Cite

Helicobacter pylori infection occurs worldwide, though the burden differs greatly between countries and within populations. Studies have shown that Helicobacter pylori infection is higher in developing countries, including Nigeria and among populations of low socio-economic status. The aim of this study was to ascertain the prevalence of Helicobacter pylori infection amongst students of Bingham University, Karu, Nassarawa State, Nigeria. A total of 565 blood samples were collected from students with their consents after completing a self-administered questionnaire. Each blood sample was spun for 5 minutes at 1000 rpm to get the serum, which was used to determine the presence of H. pylori antibody using a Helicobacter pylori test cassette. Of the 565 students screened, 31 were found to be positive, giving a prevalence of 5.5% (95%CI=3.6-7.4). Prevalence among the female students was higher at 6.3% in contrast to the male 4.5%, though this difference was not statistically significant (chi-square=0.904, P-value=0.34). Students aged 26-30 years showed the highest prevalence of 8.8% above 4.2%, 5.6% of the age ranges 15-20 and 21-25 years, respectively. Seropositivity of H. pylori increased with students’ year of study, with 100 Level having 9.3%, followed by 6.3% in 200 level. The 300 and 400 Levels had 5.8% and 2.5, respectively. Also, the students who were knowledgeable about the infection and those who were not had 15.7% and 3.2% seroprevalence, respectively. The low prevalence of the infection obtained in this study did not show sex or age differencesand could be as a result of the good sanitary living conditions or good feeding habits of the students. It is recommended that infected students should eat at regular intervals, obtain adequate treatment after stool analysis to confirm the infection, and also practice good sanitary habits. The school authority should keep on improving the living conditions of the students as this will enhance lower prevalence or total elimination of the infection.

show abstract

“…Although these two values were not big, most individuals were infected by H. pylori at a young age without symptoms. 29,30 And the global prevalence of infection was high, especially in developing countries where it exceeded 50%. 1 Spontaneous H. pylori eradication occurred in infants and children, but the eradication rate decreased with age.…”

Section: Discussionmentioning

confidence: 99%

Persistent Helicobacter pylori infection for more than 3 years leads to elevated serum homocysteine concentration: A retrospective cohort study based on a healthy Chinese population

Chen

et al. 2021

J of Gastro and Hepatol

View full text Add to dashboard Cite

Background and Aim:The relationship between the Helicobacter pylori (H. pylori) infection and homocysteine is unclear. We evaluated the effect of H. pylori on serum homocysteine in a healthy Chinese population. Methods: A total of 21 184 individuals aged over 18 years underwent 13 C/ 14 C urease breath test ( 13 C/ 14 C-UBT) and blood tests and 5042 individuals with follow-up intervals greater than 6 months. Homocysteine levels are classified according to the Chinese expert consensus. Results:The rates of H. pylori infection of normal level, mild level, moderate level, and severe level were 40.9%, 43.8%, 45.8%, and 46.6%, respectively (P = 0.000). H. pylori infection increased the risk of higher homocysteine concentration (OR = 1.406, P = 0.000).In the case-control study, the rates of persistent negative, new infection, persistent infection, and eradication infection were 43.6%, 11.2%, 22.9%, and 22.3%, respectively. The percentage of changes in serum homocysteine levels varied significantly among the different H. pylori infection statuses only in mild level (P = 0.024). Mean changed homocysteine values were higher in the subgroup of persistent infection than in the persistent negative subgroup (P = 0.004) and the eradication infection subgroup (P = 0.034). Serum homocysteine values were elevated only in the subgroup with over 3 years interval time and persistent infection (n = 107, mean paired differences = 1.1 ± 4.6 μmol/L, P = 0.014). Conclusions: There is a relationship between H. pylori and serum homocysteine, and persistent infection leads to elevation of the latter.

show abstract

Changing prevalence of Helicobacter pylori infection in children and adolescents

Cited by 39 publications

References 35 publications

The global prevalence of and factors associated with Helicobacter pylori infection in children: a systematic review and meta-analysis

The global prevalence of and factors associated with Helicobacter pylori infection in children: a systematic review and meta-analysis

Seroprevelance of Helicobacter pylori Infection among Students of Bingham University, Karu in North-Central Nigeria

Persistent Helicobacter pylori infection for more than 3 years leads to elevated serum homocysteine concentration: A retrospective cohort study based on a healthy Chinese population

Contact Info

Product

Resources

About