Changing Patterns of Treatment and Survival in Neonates With Meconium Ileus

Comparison of T Tube Ileostomy and Bishop Koop Ileostomy for the Management of Uncomplicated Meconium Ileus

“…This result matches with the study of Rescorla where survival at 1 year was 92% in patients with uncomplicated meconium ileus [11]. Recently, Ziegler had quoted 95-100% survival of neonates with meconium ileus and had accredited it to optimum surgical, pulmonary and nutritional care [1].…”

Primary resection and anastomosis for complicated meconium ileus: a safe procedure?

“…MI affects about 10% of patients with cystic fibrosis (CF) and could be the first presenting symptom of the condition [1]. Generally, MI can be classified into two forms: uncomplicated cases in which a simple intraluminal ileal obstruction occurs and complicated cases that are related to mechanical complications of the meconium bolus [2]. Several methods have been used successfully in the treatment of uncomplicated MI.…”

Clinical outcome of cystic fibrosis presenting with or without meconium ileus: a matched cohort study

“…Before 1970, patients with MI had a high operative mortality rate (up to 70%), and the long-term survival was significantly lower, compared with non-MI CF patients [1][2][3][4]. The introduction of diatrizoate meglumine (Gastrografin) enema as a nonoperative form of treat ment in uncom plicated cases of MI [5] and the improvement of surgical techniques, combined with better neonatal postoperative care in the remaining patients with complications (atresia, volvulus, perforation, failure of Gastrografin), allowed between 86% and 100% of survi val [2,6,7] .The management of neonates with MI required a multidisciplinary approach with appropriate nutritional support and optimal pulmonary care. The present study evaluated the clinical characteristics, genotype, and complications and compared long-term nutritional and pulmonary 0022-3468/$ -see front matter D…”