Changing Patterns in the Prevalence of Dementia in a Japanese Community: The Hisayama Study

Kiyohara, Yutaka; Yoshitake, Taketo; Kato, Isao; Ohmura, Takao; Kawano, Hideo; Ueda, Kazuo; Fujishima, Masatoshi

doi:10.1159/000213625

Cited by 63 publications

(57 citation statements)

References 14 publications

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“…Para as variáveis "prevalência de demência", "idade", "gênero" e razão "doença de Alzheimer / demência vascular" foram utilizados, respectivamente, 22 5,8,[10][11][12][13]15,17,[20][21][22][23][24]26,29,30,32,34,37,38,41,42 considerados como citações da mesma entidade nosológica os termos doença de Alzheimer, demência de Alzheimer, demência do tipo Alzheimer e demên-cia senil do tipo Alzheimer. O mesmo critério foi utilizado para os termos demência vascular, demência isquêmica vascular e demência por múltiplo infarto.…”

Section: Resultsunclassified

“…Uma importante inversão desta relação ocorreu em 30% dos estudos asiáticos, com a prevalência de DV relatada em dois estudos 11,12 como 2 vezes maior do que a de DA. O efeito da idade sobre estes dois diagnósti-cos etiológicos também pôde ser observado ao se constatar que houve aumento importante da relação DA/DV nos centenários (Fig 2).…”

Section: Resultsunclassified

“…Kiyohara et al 12 , embora tenham encontrado um predomínio de DV sobre DA, constataram aumento significativo na razão DA/DV em um período de 7 anos.…”

Section: Resultsunclassified

“…Entretanto, chama a atenção o fato de que 13 5,[11][12][13]15,[21][22][23][24]29,32,34,38 dos 21 estudos que informaram a prevalência geral de demência, acima dos 65 anos, investigando 38.318 idosos na comunidade, encontraram taxas que variaram de 4,2% a 7,2%. Portanto, parece existir tendência a uma aproximação das taxas de prevalência geral de demência acima dos 65 anos em todo o mundo (os 13 estudos citados foram realizados em todas as regiões pesquisadas, excetuando-se a África).…”

Section: Discussionunclassified

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Prevalência de demência em diversas regiões do mundo: Análise dos estudos epidemiológicos de 1994 a 2000

Lopes

Bottino

2002

Arq. Neuro-Psiquiatr.

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-Objective: To analyse the prevalence studies of dementia from 1994 to 2000. Methods: The papers were searched on Medline and Lilacs and the inclusion criteria were: to be an original study, that estimated dementia prevalence and investigated community samples. Results: thirty-eight studies were evaluated from all continents. The mean age-specific prevalence rates of dementia were 1,17% for the 65-69 years group, and 54,83% over 95 years. The results were strongly influenced by age. Dementia prevalence rates were higher on women on 75% of the papers reviewed. The Alzheimer's disease/vascular dementia ratio was higher in South America and lower in Asia. Discussion: Methodological advances were found, specially regarding the homogeneity of diagnostic criteria. The effect of age on the rates of dementia prevalence was pronounced, up to 90 years of age. 2 , em importante revisão da literatura, observaram esta tendência, destacando que a prevalência de demên-cia dobrava a cada 5 anos de aumento da faixa etária. No entanto, a distribuição destes quadros apresentou-se de forma diferente em vários países. Entre estas diferenças, destacou-se a maior frequência de casos de demência vascular do que de doença de Alzheimer nos estudos japoneses, quando comparados aos ocidentais. Aspectos metodológicos foram considerados para tentar justificar estas dife-

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Section: Resultsunclassified

“…Kiyohara et al 12 , embora tenham encontrado um predomínio de DV sobre DA, constataram aumento significativo na razão DA/DV em um período de 7 anos.…”

Section: Resultsunclassified

Section: Discussionunclassified

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Prevalência de demência em diversas regiões do mundo: Análise dos estudos epidemiológicos de 1994 a 2000

Lopes

Bottino

2002

Arq. Neuro-Psiquiatr.

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“…Stroke is a leading cause of death 1 and permanent disability in middleaged and elderly people in Japan [2][3][4] as well as in other developed countries. 5 In Japan, the prevalence of obesity has increased rapidly along with the westernization of lifestyle, 6 although it remains considerably lower than that in Western populations.…”

Section: Introductionmentioning

confidence: 99%

Body mass index and stroke incidence in a Japanese community: the Hisayama study

et al. 2010

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Although obesity is one of the major risk factors for coronary heart disease, its role in the development of stroke remains controversial. A total of 2421 residents, aged 40-79 years of a Japanese community were followed up prospectively for 12 years. The subjects were divided into four groups according to body mass index (BMI) levels (o21.0, 21.0-22.9, 23.0-24.9 and X25.0 kg m À2 ). During the follow-up, 107 ischemic and 51 hemorrhagic strokes occurred. The age-adjusted incidence of ischemic stroke for men significantly increased with increasing BMI levels (P for trend¼0.005). This association remained substantially unchanged even after adjustment for other risk factors: namely, systolic blood pressure, electrocardiogram abnormalities, diabetes, total cholesterol, high-density lipoprotein-cholesterol, triglycerides, smoking habits, alcohol intake and regular exercise (P for trendo0.001). Compared with that of the BMI levels of o21.0 kg m À2 , the multivariate-adjusted risk of ischemic stroke was significant even in the BMI levels of 23.0-24.9 kg m À2 (multivariate-adjusted hazard ratio (HR)¼3.12; 95% confidence interval (CI), 1.24-7.87; P¼0.02) as well as in the BMI levels of X25 kg m À2 (multivariate-adjusted HR¼5.59; 95% CI, 2.09-14.91; Po0.001). In stratified analyses, the risk of ischemic stroke for men synergistically increased in subjects having both obesity and diabetes or a smoking habit. We found no significant associations between BMI levels and ischemic stroke in women and between BMI levels and hemorrhagic stroke in either sex. In conclusion, our findings suggest that overweight and obesity are independent risk factors for ischemic stroke in Japanese men.

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Gender Comparisons of Cognitive Performances Among Vascular Dementia, Alzheimer Disease, and Older Adults Without Dementia

Jg¹,

Aa²,

McCleary³

et al. 1996

Archives of Neurology

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Changing Patterns in the Prevalence of Dementia in a Japanese Community: The Hisayama Study

Cited by 63 publications

References 14 publications

Prevalência de demência em diversas regiões do mundo: Análise dos estudos epidemiológicos de 1994 a 2000

Prevalência de demência em diversas regiões do mundo: Análise dos estudos epidemiológicos de 1994 a 2000

Body mass index and stroke incidence in a Japanese community: the Hisayama study

Gender Comparisons of Cognitive Performances Among Vascular Dementia, Alzheimer Disease, and Older Adults Without Dementia

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