Changing of Uric Acid Levels by Age and Sex in Patients with Diabetes Mellitus

Basaran, Nilgün; Evliyaoğlu, Osman; Sucu, Veysel; Dikker, Okan; Bulut, Leyla; Tezcan, Fatma; Kalaslıoğlu, Vesile; Sandıkçı, Rıza; Vardar, Müberra

doi:10.5799/ahinjs.01.2016.01.0561

Cited by 2 publications

(2 citation statements)

References 6 publications

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“…33 Estrogen hormone plays an important role in the regulation of serum UA through the removal of more urate from the kidney, secondary to reabsorption. 27,51,52 The strengths and limitations of our study need to be addressed. This is a population-based cross-sectional study with strict training process and quality assurance programs.…”

Section: Discussionmentioning

confidence: 99%

Relationship Between Metabolic Syndrome and Serum Uric Acid in an Iranian Community Elderly Population: A Cohort Aging Study

Babaei

Bakhtiari

Divband

et al. 2019

J Apple Biotechnol Rep

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Section: Discussionmentioning

confidence: 99%

Relationship Between Metabolic Syndrome and Serum Uric Acid in an Iranian Community Elderly Population: A Cohort Aging Study

Babaei

Bakhtiari

Divband

et al. 2019

J Apple Biotechnol Rep

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“…It has been indicated that that elevated serum uric acid (SUA) level is an independent risk factor for the mortality of cardiovascular disease [ 3 ]. SUA level is also an independent risk factor for type 2 diabetes mellitus (T2DM) [ 4 , 5 ]. Elevated SUA levels have been associated with coronary artery disease and also with fasting glucose [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

Effects of rosuvastatin on serum glucose and insulin in hyperuricemic rats

Xilifu

Tuerxun

Nuermaimaiti

et al. 2022

BMC Pharmacol Toxicol

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Background Hyperuricemia is a state in which the serum levels of uric acid (UA) are elevated. This study was to determine the roles of rosuvastatin in fasting blood glucose (FGB) and insulin levels in hyperuricemic rats. Methods Thirty-six Sprague-Dawley (SD) rats were randomized divided into the control, model and rosuvastatin groups: the control was given no intervention, the model group was established by administrating yeast extract powder and oxonic acid potassium salt, and the rosuvastatin group was given intravenous administration of rosuvastatin for 28 days in hyperuricemic rats. Serum uric acid (SUA), fasting blood glucose (FBG), fasting blood insulin (FBI), glutamic acid decarboxylase antibody (GADA), oral glucose tolerance test (OGTT) levels, and the ultrastructure of pancreatic β-cells were measured. Also, homeostasis model assessment of insulin resistance (HOMA-IR) scores was computed in three groups. Results Compared to the model group, SUA were decreased, while the FBG, GADA, OGTT and HOMA-IR at week 4 were significantly increased in rosuvastatin group. However, FBI was not significantly changed between three groups. It was also showed that the structure of pancreatic β-cells was damaged and the number of β-cells was changed in hyperuricemic rats while they were aggravated in rosuvastatin group. Conclusion Rosuvastatin has roles in inducing FGB, GADA, OGTT and pancreatic β-cells damage in hyperuricemic rats.

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Changing of Uric Acid Levels by Age and Sex in Patients with Diabetes Mellitus

Cited by 2 publications

References 6 publications

Relationship Between Metabolic Syndrome and Serum Uric Acid in an Iranian Community Elderly Population: A Cohort Aging Study

Relationship Between Metabolic Syndrome and Serum Uric Acid in an Iranian Community Elderly Population: A Cohort Aging Study

Effects of rosuvastatin on serum glucose and insulin in hyperuricemic rats

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