Changing incidence of hip, distal radius, and proximal humerus fractures in Tottori Prefecture, Japan

Hagino, Hiroshi; Yamamoto, Kōichi; Ohshiro, Hitoshi; Nakamura, T.; Kishimoto, Hiroyuki; Nose, Takayuki

doi:10.1016/s8756-3282(98)00175-6

Cited by 187 publications

(120 citation statements)

References 35 publications

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“…Although a decline in the age-adjusted incidence rate of hip fractures was reported between 1997 and 2003 among inpatients (30,31) and US Medicare patients (32), the rate of hip fracture in the US is still higher than in non-Scandinavian countries (33)(34)(35); this finding is consistent with a previous review study (36).…”

Section: Discussionsupporting

confidence: 86%

Hip fractures in the United States: 2008 nationwide emergency department sample

Kim

Meehan²,

Blumenfeld

et al. 2012

Arthritis Care & Research

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Objective. To evaluate the recent epidemiology of hip fractures in the US. Methods. We identified hip fracture cases from the 2008 Nationwide Emergency Department Sample, which contains more than 28 million emergency department (ED) records. Results. In 2008, approximately 341,000 (95% confidence interval 323,000 -358,000) patients visited EDs with hip fractures. Of those, 90% were age >60 years. Between ages 60 -85 years, the risk of fracture doubled for every 5-to 6-year increase in age. However, the hip fracture risk increased slowly after age 85 years. The overall trochanteric-to-cervical fracture ratio was nearly 2:1. The risk of trochanteric fracture increased faster with age compared with the risk of cervical fracture. At age 85 years, the rates of trochanteric and cervical fractures (per 100,000) were 1,300 and 700, respectively, among women and 800 and 500, respectively, among men. Conclusion. The slowed growth of hip fracture risk after age 85 years suggests that the eldest old group may have a distinct hip fracture risk. Our study showed that trochanteric fractures were twice as common as cervical fractures. Because trochanteric fractures are more closely related to severe and generalized bone loss than cervical fractures, we hypothesize that the high incidence rate of trochanteric fractures in the US suggests that osteoporosis is a health problem that is linked to hip fracture. In addition to improved safety measures to reduce falls, rigorous preventive treatments of osteoporosis may be needed.

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Section: Discussionsupporting

confidence: 86%

Hip fractures in the United States: 2008 nationwide emergency department sample

Kim

Meehan²,

Blumenfeld

et al. 2012

Arthritis Care & Research

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“…Although the incidence rate of humeral fractures among elderly patients in the US is not increasing (13), the rate of humerus fractures in the US is considerably higher than that of countries with a larger proportion of elderly persons in the population. Epidemiologic studies suggest that the annual incidence rates of humerus fractures in the US are higher than those in Japan and European countries (15)(16)(17)(18)(19)(20)(21)(22) (Table 2). Finland is considered to be a country with high fragility fracture rates (23).…”

Section: Discussionmentioning

confidence: 99%

Epidemiology of humerus fractures in the United States: nationwide emergency department sample, 2008

Kim

Szabo

Marder

2012

Arthritis Care & Research

279

148

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Objective. To evaluate the occurrence of emergency department (ED) visits due to humerus fractures in the US. Methods. We analyzed the 2008 Nationwide Emergency Department Sample, which contained approximately 28 million ED records. We identified the cases of interest using diagnostic codes for proximal, shaft, and distal humerus fractures. Results. In 2008, approximately 370,000 ED visits in the US resulted from humerus fractures. Proximal humerus fractures were the most common, accounting for 50% of humerus fractures. The incidence rate of proximal humerus fractures followed the shape of an exponential function in the age groups 40 -84 years for women (R 2 ‫؍‬ 97.9%) and 60 -89 years for men (R 2 ‫؍‬ 98.2%). After the exponential increase in these age intervals, the growth rate of proximal humerus fracture slowed and eventually decreased. The peak occurrence of distal humerus fractures was in children ages 5-9 years; however, elderly women had an increased risk. As the baby boomer generation ages, unless fracture prevention programs improve, more than 490,000 ED visits due to humerus fractures are expected in 2030 when the youngest of the baby boomers turn age 65 years. Conclusion. Compared to epidemiologic studies in Japan and European countries, the incidence rates of humerus fractures are substantially higher in the US. The high incidence rate of humerus fractures in the expanding elderly population may contribute to the recent trend of rapid increase in shoulder arthroplasty in the US. Rigorous safety measures to reduce falls and improved preventive treatments of osteoporosis are needed.

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“…Although fragility fractures of the distal radius are common mostly in women in their 60s or 70s [1], treatment for osteoporosis after such fractures requires in-depth exploration. These fractures are seen to occur at a younger age in patients in comparison with other major osteoporotic fractures [2] and are the most common fractures to occur in the postmenopausal period [3].…”

Section: Introductionmentioning

confidence: 99%

Effect of Alendronate on the Healing Time of Distal Radial Fractures Treated Conservatively: An Observational Study

Koshy

Pinto

Sujir

et al. 2017

Asian J Pharm Clin Res

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Objective: Although fragility fractures of the distal radius are common, osteoporosis treatment requires exploration as attempts to improve postfracture investigations have been only partially successful. Bisphosphonates may help minimize the risk of secondary fractures but being a potent antiresorptive agent; it raises concerns about adverse effects on the healing process. This observational study examines the effect of bisphosphonate (alendronate) on healing of acute fractures of distal radius through 66 patients aged >45 years admitted to two tertiary care hospitals in Mangalore from May 2014 to September 2016. Methods:The methodology consists of purposive sampling from two groups: Control having 33 patients not on alendronate therapy and cases comprising 33 who are on alendronate as part of prophylaxis for osteoporosis before fracture occurrence, with outpatient reviews at 2-week intervals starting from the 6 th till fracture union seen. At each visit, plain radiographs of the involved wrist were taken to yield time to cortical bridging, with range of active movement of the affected wrist taken using a goniometer. Data were analyzed using Statistical Package for the Social Sciences software version 17.0 for t values, p values and correlations and results were presented in the form of graphs and tables.Results: No significant differences were observed in the groups (as per p values) w.r.t. gender (0.804), age (0.835), time to healing (1.000), dorsiflexion (0.956), palmar flexion (0.670), ulnar deviation (0.441), radial deviation (1.000), supination (0.132), or pronation (0.302). Quick Disabilities of the Arm, Shoulder and Hand score did not differ by >95% between the groups over the analysis period. Conclusion:It was observed that alendronate administration in distal radius fractures did not appear to delay fracture healing times radiologically or clinically.

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Changing incidence of hip, distal radius, and proximal humerus fractures in Tottori Prefecture, Japan

Cited by 187 publications

References 35 publications

Hip fractures in the United States: 2008 nationwide emergency department sample

Hip fractures in the United States: 2008 nationwide emergency department sample

Epidemiology of humerus fractures in the United States: nationwide emergency department sample, 2008

Effect of Alendronate on the Healing Time of Distal Radial Fractures Treated Conservatively: An Observational Study

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