1995
DOI: 10.1164/ajrccm.152.5.7582295
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Changing heat and moisture exchangers every 48 hours rather than 24 hours does not affect their efficacy and the incidence of nosocomial pneumonia.

Abstract: Heat and moisture exchangers (HME) (Dar-Hygrobac II, Peters) can safely be used every 24 h for long-term mechanical ventilation and provide a cost-saving alternative to heated humidifiers. We have prospectively determined whether changing HMEs every 48 h only affects their clinical and bacteriological efficiency in a series of consecutive nonselected ICU patients requiring long-term mechanical ventilation. Two consecutive periods were compared. During period 1, HMEs were replaced every day; during period 2, th… Show more

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Cited by 83 publications
(41 citation statements)
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“…No entanto, vários estudos questionam a frequência da troca e seu uso prolongado por mais que 24 horas 22,23,25 . Djedaini et al 29 mostraram que as propriedades de filtro bacteriológico de um FTCU não foram modificadas com o uso por 48 horas e que a incidência de PAV foi idêntica entre indivíduos que usaram por 24 ou 48 horas.…”
Section: Discussionunclassified
“…No entanto, vários estudos questionam a frequência da troca e seu uso prolongado por mais que 24 horas 22,23,25 . Djedaini et al 29 mostraram que as propriedades de filtro bacteriológico de um FTCU não foram modificadas com o uso por 48 horas e que a incidência de PAV foi idêntica entre indivíduos que usaram por 24 ou 48 horas.…”
Section: Discussionunclassified
“…We postulate that it may have some relation to a change in the humidification protocol. At the end of 1996, in an attempt at decreasing costs, we started using HMEFs for 48 h instead of the previous more conventional 24 h. This practice of using HMEFs for 48 h has been found to be safe [15,16,17,18] and recent evidence suggest that the use for 96 h too may be safe [19]. The authors of the above studies, however, conceded the need for larger studies.…”
Section: Discussionmentioning
confidence: 99%
“…The antimicrobial prescription policy, which was systematically applied by medical staff, was to prescribe the narrowest-spectrum antibiotic as soon as the susceptibility of the causative bacteria became known. For all patients, a heat-moisture exchanger was positioned between the Y-piece and the patient and was changed every 48 h [10]. The oropharyngeal cavity was carefully cleaned with antiseptic solution (hexamedine) 4 times daily.…”
Section: Study Populationmentioning
confidence: 99%