Changing Concept of Sciatica: A Historical Overview

Hashemi, Mamak; Halabchi, Farzin

doi:10.5812/ircmj.21132

Cited by 5 publications

(3 citation statements)

References 8 publications

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“…Among them, Ficus carica L. and Olea europaea L. which are widely used in traditional medicine for their benefits as metabolic, respiratory, cardiovascular, antispasmodic, anti-inflammatory, eyesore and cancer diseases remedies [5, 6, 7]. Furthermore previous studies have demonstrated the ability to inhibit the proliferation of several cancer cell lines including pancreatic [8], leukaemia [9], stomach [10], breast [11, 12, 13], prostate [14], carcinoma [15] and colorectal cancer [16]. These pharmacological properties of Ficus carica L and Oela europaea L are probably due to the presence of plant secondary metabolites, which contains several bioactive compounds [17].…”

Section: Introductionmentioning

confidence: 99%

Phytochemical screening, antioxidant activity and inhibitory potential of Ficus carica and Olea europaea leaves

Lahmadi

Hassan

Hamid³

et al. 2019

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It is our interest to screen Oela europaea L and Ficus carica L leaf extract for total phenolic, flavonoid contents and to evaluate their free radical scavenging and Ferric reducing power (FRAP) using 1,1-diphenyl-2-picrylhydrazyl (DPPH). Data shows that Olea europaea and Ficus carica have strong antioxidant potency to scavenge free radical at an optimal phenolic and flavonoid concentration. Results further suggest a strong correlation between antioxidant activities, phenolic and flavonoid contents. Thus, the screening of Ficus carica and Olea europaea leaf extracts for potential antioxidants as source of drugs for several diseases especially oxidative stress and cancers is illustrated.

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Section: Introductionmentioning

confidence: 99%

Phytochemical screening, antioxidant activity and inhibitory potential of Ficus carica and Olea europaea leaves

Lahmadi

Hassan

Hamid³

et al. 2019

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“…Oleo europaea L. and Ficuscarica L. are widely used in traditional medicine to treat metabolic, respiratory, cardiovascular, antispasmodic, anti-inflammatory, eyesore and cancer diseases [ 11 , 12 , 13 ]. Furthermore, previous studies have demonstrated the ability of these plants' extracts to inhibit the proliferation of several cancer cell lines including pancreatic [ 14 ], leukemia [ 15 ], stomach [ 16 ], breast [ 17 , 18 ], prostate [ 19 ] and colorectal cancer [ 20 ]. Several studies have reported that pharmacological properties of Ficuscarica L. and Oleaeuropaea L. are probably due to the presence of plant secondary metabolites, prevailing in several bioactive compounds, such as polyphenols, flavonoids, tannins, organic acids, coumarins, vitamin E and carotenoids [ 21 , 22 , 23 , 24 ].…”

Section: Introductionmentioning

confidence: 99%

A specific QSAR model for proteasome inhibitors from Oleaeuropaea and Ficuscarica

et al. 2018

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Oleaeuropaea and Ficuscarica are widely used in traditional medicine for the treatment of cancer. Therefore, it is of interest to develop a QSAR model for screening proteasome inhibitors from plant source. Hence, a QSAR model was developed using multiple linear regressions; partial least squares regression and principal component regression methods. Results of QSAR modeling and docking demonstrate that compounds derived from both plants have great potentiality to be proteasome inhibitors. The developed QSAR model highlights a strong structure-effect relationship. The predicted correlation of comparative molecular field analysis, and comparative molecular similarity indexes are 0.963 and 0.919, respectively. Computed absorption, distribution, metabolism, excretion and toxicity studies on these derivatives showed encouraging results with very low toxicity, distribution and absorption.

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“…A number of tests can aid in identifying sciatica and ruling out related illnesses. Homoeopathic Therapeutics [5,6,7] Ammonium mur [Am-m] A sense of contradiction or actual contradiction in the legs; long-lasting and severe Tearing, stitching, and ulcerative pains in the heels; sciatica pain on the left side as if the hip tendons were too short; and pain in the heels that is relieved entirely when lying down. He limps when walking and complains of gnawing pain in the bones while sitting.…”

Section: Testsmentioning

confidence: 99%