Changing Attitudes toward the COVID-19 Vaccine among North Carolina Participants in the COVID-19 Community Research Partnership

Enwezor, Chukwunyelu; Peacock, James E.; Seals, Austin; Edelstein, Sharon L.; Hinkelman, Amy; Wierzba, Thomas F.; Munawar, Iqra; Maguire, Patrick D.; Lagarde, William H.; Runyon, Michael S.; Gibbs, Michael; Gallaher, Thomas R; Sanders, John W.; Herrington, David M.

doi:10.3390/vaccines9080916

Cited by 4 publications

(4 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The difference in the incidence of severe adverse events across countries may be attributed to differences in the total number of vaccinations or racial differences. In terms of vaccine hesitancy, medical education or contents of mass media that reinforce confidence in the safety of novel vaccines may have led to a shift toward vaccine acceptance [22,23]. Therefore, we considered our findings to be quite important, because they support the fact that the incidence of severe adverse events is not very high.…”

Section: Discussionmentioning

confidence: 93%

Adverse Events Following Immunization Associated with the First and Second Doses of the ChAdOx1 nCoV-19 Vaccine among Healthcare Workers in Korea

Jeon

Kim

et al. 2021

Vaccines

View full text Add to dashboard Cite

As worldwide large-scale inoculation of novel vaccines is on the way, the importance of real-world data on safety cannot be overemphasized. We aimed to investigate the adverse events following immunization (AEFIs) associated with the ChAdOx1 nCoV-19 vaccine among healthcare workers (HCWs). We investigated the systemic and local adverse events reported within seven days following the first and second doses of vaccination, using the mobile vaccine adverse events reporting system (MVAERS) developed by our hospital. The response rates were 71.8% (994/1384) and 52.9% (727/1375) after the first and second doses, respectively. The most commonly reported AEFIs were tenderness and pain at the injection site and fatigue after the first and second doses. In comparison to the first dose, the incidence and severity of AEFIs were lower following the second dose. Since the Korean government does not recommend the ChAdOx1 nCoV-19 vaccination for those under 30 years of age, with greater risk than benefit, we additionally compared the AEFIs of age groups under and above 30 years of age. The overall incidence of AEFIs was similar in both the under and over 30 age groups. In conclusion, AEFIs associated with the ChAdOx1 nCoV-19 vaccine were found to be tolerable, and AEFIs associated with the second dose were less common and severe compared to the first dose. Further safety surveillance studies on COVID-19 vaccines are required to validate our findings.

show abstract

Section: Discussionmentioning

confidence: 93%

Adverse Events Following Immunization Associated with the First and Second Doses of the ChAdOx1 nCoV-19 Vaccine among Healthcare Workers in Korea

Jeon

Kim

et al. 2021

Vaccines

View full text Add to dashboard Cite

show abstract

“…Research suggests that AAs and other minority populations were more hesitant about taking the COVID-19 vaccine than their non-Hispanic White counterparts [ 33 , 34 ]. Saluja et al [ 34 ] attributed this greater prevalence of VH in Black communities (Black = 36.1% vs. White = 22.1%, p = 0.03) to government mistrust and the need to wait and observe vaccine side effects before receiving the vaccine.…”

Section: Vaccine Hesitancymentioning

confidence: 99%

The Past Is so Present: Understanding COVID-19 Vaccine Hesitancy Among African American Adults Using Qualitative Data

Majee

Anakwe

Onyeaka

et al. 2022

J. Racial and Ethnic Health Disparities

View full text Add to dashboard Cite

Background African Americans (AAs) are disproportionately affected by structural and social determinants of health, resulting in greater risks of exposure to and deaths from COVID-19. Structural and social determinants of health feed vaccine hesitancy and worsen health disparities. Objective The present study aims to explore vaccine attitudes and intentions among program participants, understand the role of an African American faith-based wellness program in COVID-19 awareness and vaccine uptake, and solicit potential solutions for this deep-rooted public health problem. Methods Data were collected through 21 in-depth interviews among individuals involved within a community-based wellness program. Sixteen phone and five in-person interviews were conducted with church leaders, lifestyle coaches, and program participants. All interviews were audio-recorded, transcribed verbatim, and inductively and thematically analyzed by three researchers. Findings Live Well by Faith (LWBF) acted as a trusted information source for COVID-19 resources for the AA community. Services provided by Live Well by Faith included enrolling community members for vaccines, negotiating vaccine provision to and facilitating the establishment of vaccine clinics at AA churches, and connecting community members to healthcare providers. Despite the role Live Well by Faith played, VH was a significant concern due, in part, to historical mistrust of government and pharmaceutical companies conducting unethical healthcare research among Black populations. Other factors included uncertainty about vaccination (vaccines’ safety, efficacy, and necessity), social media misinformation, and political affiliation. Participants expressed the need for government to commit resources towards addressing historical factors and building trust with minority populations. Conclusion Resource targeting programs such as Live Well by Faith that engage faith and community leaders in co-designed shared and culturally grounded interventions can help restore and strengthen trust in vaccines and governments and reduce vaccine hesitancy.

show abstract

“…Additionally, one study found that the COVID-19 vaccine intentions of Black individuals from the United States were initially comparable to White individuals from the United States; however, the Black individuals experienced a more rapid increase in belief that the vaccines were necessary for protection and vaccine intention over time [51]. One study from North Carolina found higher rates of vaccine uptake among older individuals (97.2% in those 70+), those with no previous COVID-19 diagnosis (92.7% vs. 81.9%), and those who lived in urban settings (urban: 94.3%; rural: 90.2%; suburban: 88.4%) [52]. Additionally, Enwezor et al found an 88.9% COVID-19 vaccine uptake among Black participants who had previously expressed negative pre-vaccination attitudes.…”

Section: Discussionmentioning

confidence: 99%

Factors Associated with COVID-19 Vaccination Promptness after Eligibility in a North Carolina Longitudinal Cohort Study

Neighbors,

Faldowski,

Pieper

et al. 2023

Vaccines

View full text Add to dashboard Cite

Many studies identified factors associated with vaccination intention and hesitancy, but factors associated with vaccination promptness and the effect of vaccination intention on vaccination promptness are unknown. This study identified factors associated with COVID-19 vaccination promptness and evaluated the role of vaccination intention on vaccination promptness in 1223 participants in a community-based longitudinal cohort study (June 2020 to December 2021). Participants answered questions regarding COVID-19 vaccination intention, vaccination status, and reasons for not receiving a vaccine. The association of baseline vaccine hesitancy with vaccination was assessed by the Kaplan–Meier survival analysis. Follow-up analyses tested the importance of other variables predicting vaccination using the Cox proportional hazards model. Older age was associated with shorter time to vaccination (HR = 1.76 [1.37–2.25] 85-year-old versus 65-year-old). Lower education levels (HR = 0.80 [0.69–0.92]), household incomes (HR = 0.84 [0.72–0.98]), and baseline vaccination intention of ‘No’ (HR = 0.16 [0.11–0.23]) were associated with longer times to vaccination. The most common reasons for not being vaccinated (N = 58) were vaccine safety concerns (n = 33), side effects (n = 28), and vaccine effectiveness (n = 25). Vaccination campaigns that target populations prone to hesitancy and address vaccine safety and effectiveness could be helpful in future vaccination rollouts.

show abstract

Changing Attitudes toward the COVID-19 Vaccine among North Carolina Participants in the COVID-19 Community Research Partnership

Cited by 4 publications

References 6 publications

Adverse Events Following Immunization Associated with the First and Second Doses of the ChAdOx1 nCoV-19 Vaccine among Healthcare Workers in Korea

Adverse Events Following Immunization Associated with the First and Second Doses of the ChAdOx1 nCoV-19 Vaccine among Healthcare Workers in Korea

The Past Is so Present: Understanding COVID-19 Vaccine Hesitancy Among African American Adults Using Qualitative Data

Factors Associated with COVID-19 Vaccination Promptness after Eligibility in a North Carolina Longitudinal Cohort Study

Contact Info

Product

Resources

About