Changes on Adipose Tissue Distribution After Laparoscopic Roux-en-Y Gastric Bypass in Obese Göttingen Minipig. Effects on Glucose Metabolism

Hurtado, Laura Hernández; Sánchez‐Margallo, Francisco M.; Vigo, J.L. De la Cruz; Antequera, Juan Maestre; Azevedo, Ana M. Matos; Casado, Javier G.; Dı́az-Güemes, Idoia

doi:10.1007/s11695-016-2223-z

OBES SURG

2016

DOI: 10.1007/s11695-016-2223-z

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Changes on Adipose Tissue Distribution After Laparoscopic Roux-en-Y Gastric Bypass in Obese Göttingen Minipig. Effects on Glucose Metabolism

Laura Hernández Hurtado

Francisco M. Sánchez‐Margallo

J.L. De la Cruz Vigo³

et al.

Abstract: The improvement in glucose metabolism seems to occur by means of the redistribution of body fat. In order to fully confirm this hypothesis, more studies including the evaluation of incretins and inflammatory molecules, as well as a glycaemia control study against glucose load, are needed.

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2024

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Cited by 2 publications

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Fecal microbiota characterization in a swine model undergoing experimental bariatric surgery sand clock with gastro-jejunal bypass

Martínez,

Berrio,

Rangél

et al. 2024

Arq. Bras. Med. Vet. Zootec.

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Bariatric surgery induces a variety of changes, including changes in the composition of the gut microbiota. The investigation evaluated the effect of the experimental gastrojejunal bypass bariatric surgery hourglass (EBSSC G-YB) on the fecal bacterial microbiota in obese Landrace pigs. Twelve six-month-old animals were used, which were supplemented with energy from 2.5 months for a period of 120 days, enough time to reach the condition. Subsequently, they were intervened with the EBSSC G-YB and the changes in the microbiota were characterized, comparing an experimental group with two control groups in a period of 30 days. The result was that the microbiota of the three groups showed Proteobacteria, Firmicutes and Bacteroidetes as the ones with the highest relative abundance, however, at the end of the experiment a difference is highlighted, where the Phylum Spirochaetes was constant and more frequently in the experimental group, while for control groups 1 and 2 it was the Phylum Tenericutes. Although the differences were not significant, qualitatively there was greater diversity in the experimental group, with greater abundance of Escherichia-Shigella and Pseudohongiella, which may be useful as quantifiable biomarkers of weight loss in future research.

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Fecal microbiota characterization in a swine model undergoing experimental bariatric surgery sand clock with gastro-jejunal bypass

Martínez,

Berrio,

Rangél

et al. 2024

Arq. Bras. Med. Vet. Zootec.

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Zoometría en cerdos obesos intervenidos con cirugía bariátrica experimental reloj de arena con derivación gastro-yeyunal

Martinez Martinez,

Pérez B,

Lancheros S

2024

Rev MVZ Córdoba

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Objetivo. Evaluar variables zoométricas en cerdos Landrace obesos intervenidos con la cirugía bariátrica experimental reloj de arena con derivación gastro-yeyunal (CBERADG-Y). Materiales y métodos. La evaluación se realizó en tres fases con 12 animales puros divididos en un grupo experimental y dos grupos control. Fase 1: inducción de obesidad alcanzada en 120 días. Fase 2: práctica de la cirugía experimental. Fase 3: evaluación de variables zoométricas [masa corporal (MC), longitud occipito-coccígea (L Occ-Co), diámetro abdominal (DA) e índice de masa corporal (IMC)] en los cerdos del experimento; comparando medidas al día cero, día 15 y día 30 entre grupos e intra-grupo. Resultados. Al final del estudio, el grupo experimental redujo la MC, el DA y el IMC sin afectar la L Occ-Co, mientras que los dos grupos control mantuvieron estables estas variables. Conclusiones. Pese a no existir diferencias significativas entre grupos, se logró estandarizar una cirugía bariátrica que influyó cuantitativamente sobre las variables zoométricas del grupo experimental.

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Changes on Adipose Tissue Distribution After Laparoscopic Roux-en-Y Gastric Bypass in Obese Göttingen Minipig. Effects on Glucose Metabolism

Abstract: The improvement in glucose metabolism seems to occur by means of the redistribution of body fat. In order to fully confirm this hypothesis, more studies including the evaluation of incretins and inflammatory molecules, as well as a glycaemia control study against glucose load, are needed.

Cited by 2 publications

References 19 publications

Fecal microbiota characterization in a swine model undergoing experimental bariatric surgery sand clock with gastro-jejunal bypass

Fecal microbiota characterization in a swine model undergoing experimental bariatric surgery sand clock with gastro-jejunal bypass

Zoometría en cerdos obesos intervenidos con cirugía bariátrica experimental reloj de arena con derivación gastro-yeyunal

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