We studied the predictors and patterns of high-sensitivity cardiac troponin T (hs-cTnT) C ardiac troponin T (cTnT) is a highly sensitive and specific biomarker for the diagnosis of acute myocardial infarction (AMI).1 However, elevated cTnT is also seen in other cardiac and noncardiac conditions. 2-5 It has therefore been proposed that the diagnosis of AMI should be made depending on changes in cTnT level in an appropriate clinical situation, to distinguish ischemic from nonischemic causes of cTnT elevation. 6 In addition, recently available high-sensitivity troponin assays can reliably detect much lower concentrations of troponin than older assays could. However, minor changes or elevations in cTnT levels without other evidence for AMI can be confusing.Paroxysmal supraventricular tachycardia (PSVT) has been identified as a probable cause of troponin elevation in the absence of severe ischemic heart disease (IHD). 7,8 This can mislead clinicians in the management of PSVT. Therefore, defining the kinetic effects of troponin elevation, especially high-sensitivity troponin, as well as the predictors of elevation, is important for straightforward clinical diagnosis of a possible underlying ischemic condition.In this study, we had 2 goals: to identify predictors of high-sensitivity cardiac troponin T (hs-cTnT) elevation; and to determine the pattern of changes in hs-cTnT levels in PSVT patients who had elevated hs-cTnT levels (with or without IHD) upon presentation at the emergency department of our tertiary-care cardiovascular center.
Patients and MethodsDuring calendar year 2013, we prospectively enrolled consecutive patients (age, >30 yr) who were admitted to the emergency department