Changes in visual quality with soft contact lenses after the instillation of hyaluronic acid eye drops

Carpena-Torres, Carlos; Pastrana, Cristina; Rodríguez-Pomar, Candela; Serramito, María; Batres, Laura; Carracedo, Gonzalo

doi:10.1016/j.clae.2021.101471

Cited by 2 publications

(4 citation statements)

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“…In this regard, a previous publication of our research group under the same experimental design and sample found that the instillation of hyaluronic acid also had either a beneficial or detrimental effect on visual quality depending on the concentration of this molecule and contact lens material. 15 Specifically, the instillation of 0.1% and 0.2% hyaluronic acid temporarily improved visual acuity with the hydrogel contact lenses, while 0.3% hyaluronic acid deteriorated visual acuity during silicone-hydrogel contact lens wear.…”

Section: Discussionmentioning

confidence: 91%

“…contact lens material. 15 Specifically, the instillation of 0.1% and 0.2% hyaluronic acid temporarily improved visual acuity with the hydrogel contact lenses, while 0.3% hyaluronic acid deteriorated visual acuity during silicone-hydrogel contact lens wear.…”

Section: Discussionmentioning

confidence: 91%

“…Sample size calculations were conducted based on the previous publications of this research project, 15,16 which previously established both high-contrast and low-contrast visual acuities as the main variables.…”

Section: Discussionmentioning

confidence: 99%

“…This study presents similar design, participants, and methods to those previously evaluating the changes in visual quality with soft contact lenses after the instillation of hyaluronic acid eye drops 15 and the stabilization of comfort and visual quality after the insertion of soft contact lenses. 16…”

Section: Methodsmentioning

confidence: 99%

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Improvement of Soft Contact Lens Wettability After the Instillation of Hyaluronic Acid Eye Drops

Pastrana

Carpena-Torres

Rodríguez-Pomar

et al. 2022

Eye &Amp; Contact Lens: Science &Amp; Clinical Practice

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To evaluate the effect of the topical instillation of hyaluronic acid eye drops with different viscosity on soft contact lens wettability and comfort. Methods: A randomized and participant-masked study was performed, involving 20 participants (25.462.6 years). One eye wore hydrogel (ocufilcon D) contact lenses, and another eye wore silicone-hydrogel (somofilcon A) contact lenses. The in vivo wettability tear film surface quality (TFSQ) index and comfort were measured before and after the instillation of different eye drops: saline solution (control) and 0.1%, 0.2%, and 0.3% hyaluronic acid. Results: Compared with saline solution, the instillation of 0.1%, 0.2%, and 0.3% hyaluronic acid improved the in vivo wettability of the hydrogel contact lenses by decreasing their TFSQ mean for 5, 10, and 30 min, respectively (P,0.05). During silicone-hydrogel contact lens wear, the hyaluronic acid did not affect wettability because there were no changes in TFSQ mean (P$0.05), but the 0.3% hyaluronic acid produced a decrease in comfort for the first 3 min (P,0.05). Conclusions: The instillation of hyaluronic acid eye drops increased the in vivo wettability of the hydrogel contact lens, and the duration of this effect was directly related to its concentration and viscosity.

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Section: Discussionmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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