Changes in Venous Blood Lactate, Venous Blood Gases, and Somatosensory Evoked Potentials after Tourniquet Application

Benzon, Honorio T.; Toleikis, J. Richard; Meagher, Laura; Shapiro, Barry A.; Ts’ao, Chung-hsin; Avram, Michael J.

doi:10.1097/00000542-198811000-00007

Cited by 58 publications

(22 citation statements)

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“…*P < 0.05 versus baseline, **P < 0.05 versus 12 h perfused as well as versus 12 h stored at 4 C. (Color version of figure is available online.) the clinical levels measured by Benzon et al, who reported that after only 36.2 min of tourniquet-time in a routine clinical setting, a mean lactate level of 28 mmol/L [55] was metabolized by the body upon tourniquet release. Interestingly, lactate levels decreased after 10 h of extracorporeal perfusion by a mean of 10%, suggesting partial metabolization by the perfused muscle in the amputated extremity.…”

Section: Discussionmentioning

confidence: 93%

Preservation of Amputated Extremities by Extracorporeal Blood Perfusion; a Feasibility Study in a Porcine Model

Constantinescu

Knall

et al. 2011

Journal of Surgical Research

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Section: Discussionmentioning

confidence: 93%

Preservation of Amputated Extremities by Extracorporeal Blood Perfusion; a Feasibility Study in a Porcine Model

Constantinescu

Knall

et al. 2011

Journal of Surgical Research

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“…Large variations in the venous 29 and body temperature. 30 In a limb affected with CRPS, venous oxygen saturation levels are excessively high. [17][18][19][20] Our findings showed that, although such elevated levels were found, even when the hand skin temperature was lower than that in the healthy hand, venous oxygen saturation did not correlate well with the regional inflammation score and/or with CRPS.…”

Section: Discussionmentioning

confidence: 99%

Delayed recovery and late development of complex regional pain syndrome in patients with an isolated fracture of the distal radius

Goris¹,

Leixnering

Huber³

et al. 2007

The Journal of Bone and Joint Surgery. British volume

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We studied prospectively the regional inflammatory response to a unilateral distal radial fracture in 114 patients at eight to nine weeks after injury and again at one year. Our aim was to identify patients at risk for a delayed recovery and particularly those likely to develop complex regional pain syndrome. In order to quantify clinically the inflammatory response, a regional inflammatory score was developed. In addition, blood samples were collected from the antecubital veins of both arms for comparative biochemical and blood-gas analysis. The severity of the inflammatory response was related to the type of treatment (Kruskal-Wallis test, p = 0.002). A highly significantly-positive correlation was found between the regional inflammatory score and the length of time to full recovery (r(2) = 0.92, p = 0.01, linear regession). A regional inflammatory score of 5 points with a sensitivity of 100% but a specificity of only 16% also identified patients at risk of complex regional pain syndrome. None of the biochemical parameters studied correlated with regional inflammatory score or predicted the development of complex regional pain syndrome. Our study suggests that patients with a distal radial fracture and a regional inflammatory score of 5 points or more at eight to nine weeks after injury should be considered for specific anti-inflammatory treatment.

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“…413 Reperfusion almost immediately relieves tourniquet pain, although a transient second phase (not usually seen with regional techniques) may ensue. 414 …”

Section: Perineural Catheter Complicationsmentioning

confidence: 99%

Upper Extremity Regional Anesthesia

Neal¹,

Gerancher

Hebl

et al. 2009

Regional Anesthesia and Pain Medicine

303

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Brachial plexus blockade is the cornerstone of the peripheral nerve regional anesthesia practice of most anesthesiologists. As part of the American Society of Regional Anesthesia and Pain Medicine's commitment to providing intensive evidence-based education related to regional anesthesia and analgesia, this article is a complete update of our 2002 comprehensive review of upper extremity anesthesia. The text of the review focuses on (1) pertinent anatomy, (2) approaches to the brachial plexus and techniques that optimize block quality, (4) local anesthetic and adjuvant pharmacology, (5) complications, (6) perioperative issues, and (6) challenges for future research.Upper extremity regional anesthesia has been a mainstay of the anesthesiologist's armamentarium since Hall 1 first reported the use of cocaine to block the brachial plexus in 1884. Recognizing that upper extremity neural blockade represents the most frequent use of peripheral nerve blocks in most anesthesiologists' practice, 2 in 2001, the American Society of Regional Anesthesia and Pain Medicine (ASRA) undertook a critical review of all available English-language publications pertinent to this topic. The resulting extensive source document was synthesized into a comprehensive review article 3 that was published in 2002; both the source and the review documents will be updated approximately every 5 years.Rather than publishing only new material that has become available since 2002, the original review article has been completely revised so that readers may continue to view the subject matter in its entirety. New topics in this review include ultrasound-guided brachial plexus block, continuous catheter-based analgesia, and a collection of new images * by medical illustrator, Jennifer Gentry (www.gentryvisualization.com). This review summarizes the essential scholarly work available from the source document, which can be viewed at Copyright © 2009 by American Society of Regional Anesthesia and Pain Medicine Address correspondence to: Joseph M. Neal, MD, 1100 Ninth Ave (B2-AN), Seattle, WA 98101 (anejmn@vmmc.org). The contents of this article are solely the responsibility of the authors and do not necessarily represent the official views of this entity. James P. Rathmell, MD, served as acting editor-in-chief for this article.Financial support: None. NIH Public Access Author ManuscriptReg Anesth Pain Med. Author manuscript; available in PMC 2010 March 1. Published in final edited form as:Reg Anesth Pain Med. 2009 ; 34(2): 134-170. doi:10.1097/AAP.0b013e31819624eb. NIH-PA Author ManuscriptNIH-PA Author Manuscript NIH-PA Author Manuscript www.asra.com. This review article strives (1) to serve as a review of pertinent anatomy, (2) to compare the effectiveness of brachial plexus approaches and techniques, (3) to present available evidence to guide selection of pharmacological agents, (4) to describe the complications inherent to upper extremity anesthesia, (5) to consider pertinent perioperative issues, and (6) to identify informational gaps and empha...

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Changes in Venous Blood Lactate, Venous Blood Gases, and Somatosensory Evoked Potentials after Tourniquet Application

Cited by 58 publications

References 0 publications

Preservation of Amputated Extremities by Extracorporeal Blood Perfusion; a Feasibility Study in a Porcine Model

Preservation of Amputated Extremities by Extracorporeal Blood Perfusion; a Feasibility Study in a Porcine Model

Delayed recovery and late development of complex regional pain syndrome in patients with an isolated fracture of the distal radius

Upper Extremity Regional Anesthesia

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