Changes in the Transcriptome Profile in Young Chickens after Infection with LaSota Newcastle Disease Virus
Taina S. B. Lopes,
Jannis Nankemann,
Cassandra Breedlove
et al.
Abstract:Understanding gene expression changes in chicks after vaccination against Newcastle Disease (ND) can reveal vaccine biomarkers. There are limited data on chicks’ early immune response after ND vaccination. Two trials focused on this knowledge gap. In experiment one, 42 13-day-old specific-pathogen-free (SPF) chicks were used. Harderian glands (Hgs) and tracheas (Tcs) from five birds per group were sampled at 12, 24, and 48 h post-vaccination (hpv) to evaluate the gene transcription levels by RNA sequencing (RN… Show more
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