Changes in the Immunological Profile of Peripheral Blood Leukocytes in Multiple Sclerosis (MS) Patients Treated with lnterferon-ß-1 a. Veränderungen des immunologischen Profils von Leukozyten im peripheren Blut von Multiple-Sklerose-(MS-)Patienten, behandelt mit lnterferon-ß-1 a
Abstract:Interferon (IFN-ß) has beneficial effects in multiple sclerosis (MS) probably by regulating the immune system. The aim of this study was to find out whether IFN-ß-la influences the immune profile of peripheral blood (PB) leukocytes in MS patients. We studied 21 outpatients (12 women and nine men; mean age: 37.2 years) with relapsing-remitting MS who had been treated with IFN-ß-la (30 fig i.m. once a week) for 9 months. Phenotype analysis of PB leukocytes was carried out using two-color flow cytometry. The foll… Show more
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