Changes in the erythrocyte anti-oxidant system of offspring of dams treated with Vitamin A and β-carotene during gestation

Kamiloğlu, Nadide Nabil; Beytut, Enver; Güven, Aysel; Altinsaat, Çiğdem

doi:10.1016/j.smallrumres.2005.06.001

Cited by 9 publications

(5 citation statements)

References 37 publications

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“…In turn, tGSH was negatively correlated with plasma carotenoid levels only among nestlings. The medical literature shows that carotenoid supplementation in the diet increases tGSH levels in mammalian tissues, including blood (e.g., Imamura et al 2006;Kamiloglu et al 2006;Serpeloni et al 2010;Gao et al 2011). However, in greenfinches (Carduelis chloris; Sepp et al 2012) and zebra finches (Costantini 2011(Costantini , 2013 significant correlations between plasma carotenoid levels and RBC tGSH or total thiols (a proxy of tGSH) were not detected.…”

Section: Discussionmentioning

confidence: 99%

Covariation in Oxidative Stress Markers in the Blood of Nestling and Adult Birds

Romero-Haro

Alonso‐Álvarez

2014

Physiological and Biochemical Zoology

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Interest in the imbalance between the production of reactive oxygen species and the state of the antioxidant machinery-that is, oxidative stress-has recently grown among comparative physiologists and evolutionary/behavioral ecologists. The number and types of markers used to estimate oxidative stress is, however, under debate. The study of covariation among these markers is necessary to better interpret the information content of each independent variable. Here, the covariation in levels of 10 blood parameters in a group of zebra finches (Taeniopygia guttata) as nestlings and adults was analyzed across a large data set. Total glutathione levels in erythrocytes were negatively correlated with plasma carotenoid values in nestlings only, supporting the implication of carotenoids in the antioxidant machinery during a particularly stressful period of life. Plasma lipid levels (triglycerides [TRGs]) as well as plasma antioxidant capacity-the latter tested with and without control for uric acid levels-showed individual consistency with age. Plasma TRG and uric acid levels were strongly correlated with plasma lipid peroxidation and antioxidant capacity, respectively, suggesting an influence of recent intake or mobilization of energy stores on these variables. The meaning of oxidative stress markers, whether corrected or uncorrected for levels of nutritional metabolites, remains to be explored. Experiments manipulating diet composition and oxidative stress are necessary to confirm or reject the hypothesized causalities.

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Section: Discussionmentioning

confidence: 99%

Covariation in Oxidative Stress Markers in the Blood of Nestling and Adult Birds

Romero-Haro

Alonso‐Álvarez

2014

Physiological and Biochemical Zoology

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“…It has been demonstrated that oxidative stress causes disorders such as placenta retention (Brzezinska-Slebodzinsk et al 1994), miscarriages, restriction of fetal growth, premature birth, and low birth weight (Al-Gubory et al 2010), as well as a higher incidence of mastitis (Bouwstra et al 2010). Thus, it is necessary to prevent it since it not only protects mothers during gestation, but may also improve the oxidative state of the offspring (Kamiloğlu et al 2006). Different studies have been conducted to determine the oxidative state in animals during gestation (Rezapour & Taghinejad-Roudbaneh 2011), near parturition (Celi et al 2010, Casamassima et al 2012 and during lactation (Pedernera et al 2010); these studies observed changes during these physiological states.…”

Section: Introductionmentioning

confidence: 99%

Oxidative state of ewes with different number of parity during gestation and lactation

et al. 2017

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This study was conducted to assess the changes in some indicators of oxidative status during pregnancy and lactation in sheep of different parity. Dorset x Suffolk ewes were classified by number of parity: 1, 2 and ≥4. They were sampled before pregnancy and on the first, second, third, and fourth months, then on day 143 of pregnancy, as well as on day 5 after birth and after one month of lactation. Antioxidant capacity was found to have two reductions, the first during the second month of pregnancy and the second on day 5 of lactation. Susceptibility to lipid oxidation decreased with an increased number of parturitions. A reduction in lipid oxidation was observed on day 143 of gestation relative to the other samplings during gestation and lactation. Total glutathione peroxidase activity increased when the two reductions in antioxidant capacity took place. Ascorbic acid decreased during lactation and gestation; the lowest values were recorded in the third month of gestation. It is concluded that susceptibility to lipid oxidation decreases with the number of parturitions and that in ewes, during gestation and lactation, there is a mechanism that prevents lipid oxidation involving changes in antioxidant capacity, glutathione peroxidase and ascorbic acid.

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“…It has also been suggested that vitamin A protects cells from damage by radicals which are believed to contribute to certain chronic diseases and play a role in the degenerative processes (Kamiloglu et al, 2005). It is regarded that vitamin A regulates immune function of animals by protection of mucosal epithelium acting as the first defense barrier (Brody, 1993) and by supporting the differentiation of epithelial cells.…”

Section: Introductionmentioning

confidence: 99%

Effects of Vitamin A on Growth Performance, Antioxidant Status and Blood Constituents in Lactating Grey Goat

Yang¹,

Wang²,

Jing³

et al. 2010

American Journal of Animal and Veterinary Sciences

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Problem statement: It is regarded that vitamin A protects cells from damage by radicals which are believed to contribute to certain chronic diseases and regulates immune function of animals by protection of mucosal epithelium acting as the first defense barrier. All these properties of vitamin A may be attributable to its antioxidant activity. This study was to evaluate the effects of different levels of vitamin A on growth performance, antioxidant status and blood constituents of lactating ewes. Approach: Thirty-two multiparous lactating ewes of Grey goat (BW = 35.1 ± 1.1 kg) were divided into four groups of eight with four different supplementing levels of vitamin A (0, 2000, 3000 and 5000 IU kg −1 DM). Ewes were fed in individual lot at ad libitum intake and had free access to water. Average daily feed intake and average milk yield of ewes were measured weekly.

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Changes in the erythrocyte anti-oxidant system of offspring of dams treated with Vitamin A and β-carotene during gestation

Cited by 9 publications

References 37 publications

Covariation in Oxidative Stress Markers in the Blood of Nestling and Adult Birds

Covariation in Oxidative Stress Markers in the Blood of Nestling and Adult Birds

Oxidative state of ewes with different number of parity during gestation and lactation

Effects of Vitamin A on Growth Performance, Antioxidant Status and Blood Constituents in Lactating Grey Goat

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