2021
DOI: 10.1111/ijfs.15475
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Changes in the content and antioxidative activity of β‐carotene and its metabolite vitamin A during gastrointestinal digestion and absorption and optimisation of HPLC‐based detection

Abstract: Summary The β‐Carotene (BC), an important precursor of vitamin A (VA), possesses antioxidant activity but is fat‐soluble and has low bioavailability. In previous in‐vitro assays evaluating antioxidant and 2,2′‐azobis(2‐amidinopropane) dihydrochloride (AAPH) free radical scavenging, both BC and VA showed a strong ability to scavenge radicals and protected cells from oxidative stress. Here, we used artificially simulated gastrointestinal digestion and Caco‐2 cell absorption models to evaluate the bioavailability… Show more

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Cited by 3 publications
(2 citation statements)
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“…A negligible low range of value (6.32E7-2.27E7 mg/100 g) was obtained for β-carotene in the entire samples; β-carotene is a precursor of vitamin A (fat-soluble). Vitamin E also belongs to a group of fat-soluble compounds formerly known as tocopherols with a welldocumented antioxidant activity (Sharif et al 2017;Zhuang et al 2022). Accordingly, despite its desirable nutritional value, yogurt is generally considered to be a poor source of fat-soluble vitamins including vitamin E (Raikos et al 2021).…”
Section: Vitamin Compositions Of Yoghurt Samplesmentioning
confidence: 99%
“…A negligible low range of value (6.32E7-2.27E7 mg/100 g) was obtained for β-carotene in the entire samples; β-carotene is a precursor of vitamin A (fat-soluble). Vitamin E also belongs to a group of fat-soluble compounds formerly known as tocopherols with a welldocumented antioxidant activity (Sharif et al 2017;Zhuang et al 2022). Accordingly, despite its desirable nutritional value, yogurt is generally considered to be a poor source of fat-soluble vitamins including vitamin E (Raikos et al 2021).…”
Section: Vitamin Compositions Of Yoghurt Samplesmentioning
confidence: 99%
“…[1] It must, however, be maintained by food or supplements due to its lipid solubility and limited bioavailability. [2] Dietary β-carotene consumption in moderation lowers the incidence of gastrointestinal cancer, atherosclerosis, bone calcification, and neuronal damage. [3][4][5] Excessive consumption, conversely, might result in carotenemia, which can impair the liver and kidney functions of patients.…”
Section: Introductionmentioning
confidence: 99%