Changes in the Composition of Carnitines in Hemodialysis Patients

Lin, Yanjuan; Wu, Yang Chang; Chen, Tzen Wen; Lin, Chih Ching

doi:10.1111/j.1523-1755.2005.00536.x

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2018

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“…Next, we calculated the removal rate of long‐chain acylcarnitine, adjusting for total protein levels before and after dialysis. We found that, similarly to previous reports, the removal rate of long‐chain acylcarnitine was lower than that of short‐chain or medium‐chain acylcarnitines, The reason for this is considered to be because long‐chain acylcarnitines have greater molecular weight and lipophilicity. However, in all patients in the present study, haemodialysis or haemodiafiltration using a high performance membrane with high β2MG (molecular weight: 11800) clearance was used.…”

Section: Discussionsupporting

confidence: 88%

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Association between resistance to erythropoiesis‐stimulating agents and carnitine profile in patients on maintenance haemodialysis

et al. 2018

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Section: Discussionsupporting

confidence: 88%

“…Because of the increased molecular weight and lipophilicity that accompanies increased chain length, we computed the extraction ratio of long‐chain aylcarnitine in consideration of blood concentration using the TP value after dialysis.…”

Section: Methodsmentioning

confidence: 99%