Changes in the composition of the excurrent duct system of the rat testis during postnatal development

Brooks, Darrell

doi:10.1530/jrf.0.0460031

Cited by 10 publications

(5 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In other studies there was also no synthesis of inositol from glucose (Eisenberg & Bolden, 1964) Robinson & Fritz (1979) exceeds the activity of phosphoglucose isomerase 12-fold (Brooks, 1976a), using the epididymal protein content given by Brooks (1976b), so loss of tritium from the Ci-position of glucose 6-phosphate during glycolysis (Hammerstedt, 1975) should be minimal, although the conflicting reports on the activity of the relevant enzymes in rat epididymal tissue (Robinson & Fritz, 1979;Maeda & Eisenberg, 1980;Hasegawa & Eisenberg, 1981) need clarification and bear directly on the results of this study. The observations may also relate to the presence of endogenous pools of metabolites which were not equilibrated during the experiments, although work on tissue slices indicates that intracellular glucose is very low in glucose-containing medium (Brooks, 1979).…”

Section: Transport Of Inositol From the Bath Into The Lumen Of The Epmentioning

confidence: 59%

Luminal secretion of myo-inositol by the rat epididymis perfused in vitro

Cooper¹,

Yeung²,

Wy³

et al. 1985

Reproduction

View full text Add to dashboard Cite

Section: Transport Of Inositol From the Bath Into The Lumen Of The Epmentioning

confidence: 59%

Luminal secretion of myo-inositol by the rat epididymis perfused in vitro

Cooper¹,

Yeung²,

Wy³

et al. 1985

Reproduction

View full text Add to dashboard Cite

“…This gives no indication of their biological (secretory) function and it certainly does not mean that the various glands are homologous to similarly named glands in eutherian mammals. The fact that between species the biochem ical homologies may be quite separate from their anatomical homologies has been stressed by Mann & Lutwak-Mann (1963, 1976.…”

Section: Discussionmentioning

confidence: 99%

“…In cases where HC104 interfered in the assays, supernatants were neutralized with 5 m K2C 03 and the precipitate of KC104 was removed by centrifugation at 0 °C (600 g, 10 min). Glycogen was extracted, purified and determined with anthrone as described by Brooks (1976).…”

Section: (E) Tissue Extractionmentioning

confidence: 99%

Structural and biochemical characteristics of the male accessory organs of reproduction in the hairy-nosed wombat(Lasiorhinus latifrons)

Brooks

Gaughwin

Mann

1978

Proc. R. Soc. Lond. B.

View full text Add to dashboard Cite

A description is given of the male reproductive tract in the South Australian marsupial, the hairy-nosed wombat, Lasiorhinus latifrons ; the study was based mainly on material obtained from animals shot in the field during the period October-December, but a few observations on captive wombats are also reported. The testes, located in a pre-penile scrotum, contained in the region of the ductuli efferentes a characteristic pigment, which occasionally extended as far as the caput epididymidis. The cauda epididymidis was enclosed within a separate pocket formed by the tunica vaginalis. The ductus deferens had no ampulla. The penis, bifid at the tip, was held in an S-bend position by the retractor penis muscles. The male accessory apparatus was of a highly complex type. In addition to the carrot-shaped prostate gland with three clearly discernible portions (anterior, central and posterior), three other pairs of glands were identified, which for the purpose of the present study have been designated as ‘Cowper’s glands’ ( A , B , and C ) without implying, however, that they are strictly analogous to the Cowper’s gland of eutherian mammals. Chemical examination of the male accessory glands led to the identification of a number of chemical substances, including fructose, sorbitol, glycogen, glucose, inositol, glycerol, citric acid, sialic acid, N -acetylglucosamine and N -acetylgalactosamine. The three most characteristic constituents of the anterior, central and posterior segments of the prostate gland were sorbitol, fructose and glycogen, respectively; the central and posterior segment of the prostate contained also some glucose and N -acetylhexosamine. Citric acid was shown to occur at high concentration in the Cowper’s gland A while the C gland was characteristically rich in sialic acid. A description is given of spermatozoa which had been recovered from the urine.

show abstract

“…Several papers described the influence of orchiectomy and EDL in the epididymis, with dramatic changes in morphology and function (Brooks, 1976;Ezer and Robaire, 2003;Fawcett and Hoffer, 1979;Turner et al, 2007a;Turner et al, 2007b). Therefore, there is a proven dependence on testicular and circulating factors for proper epididymal function (Belleannee et al, 2011a).…”

Section: Regulation Of Secretory Activity In the Epididymismentioning

confidence: 99%

The epididymis and its role on sperm quality and male fertility

Souza¹,

Schorr-Lenz²,

Lucca³

et al. 2017

Anim Reprod

View full text Add to dashboard Cite

The epididymis is a complex organ where spermatozoa acquire motility and ability to fertilize the egg. Epididymal maturation lasts 1 or 2 weeks and exposes the immature spermatozoa to a sequentially modified milieu, promoting intense interactions with secretions by the epididymal epithelium. Sperm surface modifications in response to interactions with epididymal secretions are key steps to achieve fertility ability. However, the precise molecular mechanisms that convert an immotile and infertile gamete into a highly motile cell capable of fusion with an oocyte are still unknown. Recent data on proteomics and transcriptomics of epididymal fluid and epididymosomes brought new ideas of the physiological roles of proteins and miRNAs in epididymal maturation in spermatozoa. This review focuses on the recent discoveries on epididymal fluid composition and its role on sperm maturation and preservation, linking to their survival and fertility potential.

show abstract

Changes in the composition of the excurrent duct system of the rat testis during postnatal development

Cited by 10 publications

References 26 publications

Luminal secretion of myo-inositol by the rat epididymis perfused in vitro

Luminal secretion of myo-inositol by the rat epididymis perfused in vitro

Structural and biochemical characteristics of the male accessory organs of reproduction in the hairy-nosed wombat(Lasiorhinus latifrons)

The epididymis and its role on sperm quality and male fertility

Contact Info

Product

Resources

About