Changes in the body composition of the surgical infant in the early postoperative period

The hormonal and metabolic response to stress in the neonate

“…In addition to the outlined mobilization of body fat stores, renewal of these stores has been suggested. Winthrop et al showed that body fat increased postoperatively from day 0 to day 7 from 12.9-0.6% to 14-0.6% (P <0.05) in 13 full-term infants undergoing surgery at approximately 10 days of life [162]. Although this is a small but statistically significant increase in body fat, the magnitude of the change falls within the range of experimental error for anthropometry.…”

“…Winthrop et al, in a prospective evaluation of pediatric trauma patients, demonstrated significant increases in basal metabolic rate (BMR), whole-body protein turnover, protein synthesis, and urinary nitrogen excretion [162]. These patients had a negative nitrogen balance due to the fact that protein breakdown increased relatively more than protein synthesis.…”

Measurement of Total Bodywater Volume with Deuterated Water in Newborn Infants

“…In these studies, the indicator was administered intravenously and blood samples were taken for the concentration measurements. In more recent studies, D20 or H2,sO was given orally or intragastrically and the tracer concentration in urine [4][5][6][7][8], saliva [5,9], or expired air [ 10,11 ] was used to calculate TBW.…”