“…To date, there is no unanimity in opinion among authors. While some did not find alterations in rat (Flickinger, 1972; McDonald and Scothorne, 1988), rabbit (Paufler and Foote, 1969; Flickinger, 1975a,b), and monkey (Chapman et al, 1978; Hadley and Dym, 1983), others reported marked changes in mouse (Singh and Chakravarty, 2000), rat (Flickinger et al, 1986, 1987, 1990; McDonald et al, 1996; Sarrat et al, 1996; Aydos et al, 1998; Whyte et al, 2000), hamster (Hamasaki et al, 1991; Sun et al, 1992), guinea pig (Hutson et al, 1976; Tung and Alexander, 1977), rabbit (Swanson and Hafs, 1969; Hooker, 1980), dog (Antypas et al, 1994), and monkey (Lohiya et al, 1987).…”