Changes in Technique and Indications for Keratoplasty in Poland, 1989 to 2014: An Analysis of Corneal Transplantations Performed at Saint Barbara Hospital, Trauma Center, Sosnowiec, Poland

Jankowska-Szmul, Judyta; Dobrowolski, Dariusz; Krysik, Katarzyna; Kwas, J.; Nejman, M.; Wylęgała, Edward

doi:10.1016/j.transproceed.2016.01.056

Cited by 9 publications

(5 citation statements)

References 31 publications

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“…Corneal elastic modulus has been reported to be lower in keratoconus patients [2] and shown increased after corneal refractive surgery [7]. Corneal biomechanical properties also changed significantly after corneal transplantation [4–6]. One could calculate corneal elastic modulus, for example, based on our method from Corvis results thoroughly.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of corneal elastic modulus based on Corneal Visualization Scheimpflug Technology

et al. 2019

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Background Corneal biomechanical properties are important for the diagnosis of corneal diseases, individualized design and prognosis of corneal surgery. Clinical available devices such as Ocular Response Analyzer (ORA) and Corneal Visualization Scheimpflug Technology (Corvis ST) can provide corneal biomechanics related parameters, while corneal elastic modulus cannot be extracted directly from them at present. The aim of this study is to suggest a method to determine corneal elastic modulus based on the results of Corvis ST test according to Reissner’s theory on the relation between stress and small displacement in shallow spherical shell. Results Five rabbits (10 eyes) and 10 healthy humans (20 eyes) were measured with Corvis ST to obtain the normal range of corneal elastic modulus. Results showed Corneal elastic modulus of rabbit was 0.16 MPa to 0.35 MPa, human corneal elastic modulus was 0.16–0.30 MPa. Rabbit corneas were also measured at different intraocular pressures (IOP), and results showed corneal elastic modulus, first applanation time (A1T) and stiffness parameter (SP-A1) were positively correlated with IOP. Deformation amplitude (DA), the second applanations time (A2T), and peak distance (PD) were negatively correlated with IOP. Finite element method was used to simulate the Corvis measurements according to the calculated elastic modulus and the simulated corneal apical displacements were agreement with experimental results in general. Conclusions The method to determine corneal elastic modulus based on Corvis test according to the relationship between force and displacements of shallow spherical shell is convenient and effective.

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Section: Discussionmentioning

confidence: 99%

Evaluation of corneal elastic modulus based on Corneal Visualization Scheimpflug Technology

et al. 2019

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“…However, in the event of PKIK, the use of topical corticosteroids may act as a double-edged sword as it can worsen the infection during the acute phase, particularly in fungal infection. Furthermore, there has been a paradigm shift in keratoplasty in the past decade where lamellar keratoplasty such as deep anterior lamellar keratoplasty (DALK), Descemet stripping automated endothelial keratoplasty (DSAEK), pre-Descemet's endothelial keratoplasty (PDEK), and Descemet membrane endothelial keratoplasty (DMEK) have superseded penetrating keratoplasty (PKP) as the preferred choice of keratoplasty for anterior and posterior corneal pathologies (13)(14)(15)(16)(17)(18)(19). However, this has also resulted in a number of complications that are not usually observed following PKP, including graft detachment and interface infectious keratitis (IIK) (20)(21)(22)(23).…”

Section: Introductionmentioning

confidence: 99%

Post-keratoplasty Infectious Keratitis: Epidemiology, Risk Factors, Management, and Outcomes

et al. 2021

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Post-keratoplasty infectious keratitis (PKIK) represents a unique clinical entity that often poses significant diagnostic and therapeutic challenges. It carries a high risk of serious complications such as graft rejection and failure, and less commonly endophthalmitis. Topical corticosteroids are often required to reduce the risk of graft rejection but their use in PKIK may act as a double-edged sword, particularly in fungal infection. The increased uptake in lamellar keratoplasty in the recent years has also led to complications such as graft-host interface infectious keratitis (IIK), which is particularly difficult to manage. The reported incidence of PKIK differs considerably across different countries, with a higher incidence observed in developing countries (9.2–11.9%) than developed countries (0.02–7.9%). Common risk factors for PKIK include the use of topical corticosteroids, suture-related problems, ocular surface diseases and previous corneal infection. PKIK after penetrating keratoplasty or (deep) anterior lamellar keratoplasty is most commonly caused by ocular surface commensals, particularly Gramme-positive bacteria, whereas PKIK after endothelial keratoplasty is usually caused by Candida spp. Empirical broad-spectrum antimicrobial treatment is the mainstay of treatment for both PKIK, though surgical interventions are required in medically refractory cases (during the acute phase) and those affected by visually significant scarring (during the late phase). In this paper, we aim to provide a comprehensive overview on PKIK, encompassing the epidemiology, risk factors, causes, management and outcomes, and to propose a treatment algorithm for systematically managing this challenging condition.

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“…In the Corvis ST tonometer, the basics of biomechanical parameters measurements are based on the analysis of the dynamic corneal deformation recorded by the ultra-fast Scheimpflug camera. Thanks to the possibility of reconstructing the full process of corneal deformation and observation of its dynamic changes in the video, the Corvis ST tonometer allows to obtain a much bigger number of quantitative parameters that are the basis for the description of biomechanical changes during the examination [32–36]. Various methods of image analysis and processing [37–39], or artificial intelligence methods and others [40–42] can be applied for this purpose.…”

Section: Introductionmentioning

confidence: 99%

Novel dynamic corneal response parameters in a practice use: a critical review

Jędzierowska

Koprowski

2019

BioMed Eng OnLine

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Background Non-contact tonometers based on the method using air puff and Scheimpflug’s fast camera are one of the latest devices allowing the measurement of intraocular pressure and additional biomechanical parameters of the cornea. Biomechanical features significantly affect changes in intraocular pressure values, as well as their changes, may indicate the possibility of corneal ectasia. This work presents the latest and already known biomechanical parameters available in the new offered software. The authors focused on their practical application and the diagnostic credibility indicated in the literature. Discussion An overview of available literature indicates the importance of new dynamic corneal parameters. The latest parameters developed on the basis of biomechanics analysis of corneal deformation process, available in non-contact tonometers using Scheimpflug’s fast camera, are used in the evaluation of laser refractive surgery procedures, e.g. LASIK procedure. In addition, the assessment of changes in biomechanically corrected intraocular pressure confirms its independence from changes in the corneal biomechanics which may allow an intraocular pressure real assessment. The newly developed Corvis Biomechanical Index combined with the corneal tomography and topography assessment is an important aid in the classification of patients with keratoconus. Conclusion New parameters characterising corneal deformation, including Corvis Biomechanical Index and biomechanical compensated intraocular pressure, significantly extend the diagnostic capabilities of this device and may be helpful in assessing corneal diseases of the eye. Nevertheless, further research is needed to confirm their diagnostic pertinence.

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Changes in Technique and Indications for Keratoplasty in Poland, 1989 to 2014: An Analysis of Corneal Transplantations Performed at Saint Barbara Hospital, Trauma Center, Sosnowiec, Poland

Cited by 9 publications

References 31 publications

Evaluation of corneal elastic modulus based on Corneal Visualization Scheimpflug Technology

Evaluation of corneal elastic modulus based on Corneal Visualization Scheimpflug Technology

Post-keratoplasty Infectious Keratitis: Epidemiology, Risk Factors, Management, and Outcomes

Novel dynamic corneal response parameters in a practice use: a critical review

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