Changes in subset distribution and impaired function of circulating natural killer cells in patients with colorectal cancer
Shujin Zu,
Yan Lu,
Rui Xing
et al.
Abstract:Natural killer (NK) cells are closely associated with malignant tumor progression and metastasis. However, studies on their relevance in colorectal cancer (CRC) are limited. We aimed to comprehensively analyze the absolute counts, phenotypes, and function of circulating NK cells in patients with CRC using multiparametric flow cytometry. The distribution of NK cell subsets in the peripheral circulation of patients with CRC was significantly altered relative to the control group. This is shown by the decreased f… Show more
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