Changes in Retinal Vasculature and Thickness after Small Incision Lenticule Extraction with Optical Coherence Tomography Angiography

Chen, Minjie; Dai, Jinhui; Gong, Lan

doi:10.1155/2019/3693140

Cited by 16 publications

(14 citation statements)

References 29 publications

(36 reference statements)

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“…Vessel density changes were assumed by the suction effects during surgery on the retinal microcirculation, and instantaneous changes in suction may cause ischaemia-reperfusion injury [ 11 ]. IOP elevation during surgery also caused a decrease in ocular blood flow [ 24 ]. In a study on healthy people by increasing IOP, researchers found that transient elevation of IOP altered optic nerve head topography [ 25 ].…”

Section: Discussionmentioning

confidence: 99%

Short-term changes in the anterior segment and retina after small incision lenticule extraction

et al. 2020

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Background To analyse short-term changes in the anterior segment and retina after small incision lenticule extraction (SMILE). Methods Patients with myopia scheduled for SMILE were recruited from Ruijin Hospital, Shanghai, China. Basic patient information such as age, sex, and refractive errors was recorded. Ocular measurements were taken before surgery, and 1 day and 1 week after surgery; they included axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), white to white (WTW), pupil diameter (PD), macular thickness (MT), ganglion cell layer thickness (GCL), retinal nerve fiber layer thickness (RNFL), choroidal thickness (CT), macular vessel density, and optic disc vessel density. Results Sixty-one eyes of 31 patients were selected for this study. AL, CCT, ACD, and postoperative PD were significantly reduced (p < 0.05), while LT was thickened after surgery (p < 0.05). MT at the fovea decreased 1 day and 1 week after surgery (p < 0.05). GCL showed no significant changes after surgery. RNFL was unchanged 1 day after surgery, but the inferior sector was thickened 1 week after surgery. CT was thicker at the fovea 1 day after surgery and 1.0 mm from the fovea in the nasal sector 1 week after surgery. Macular vessel density was significantly decreased 1 day after surgery and most recovered in 1 week. Optic disc vessel density decreased at the peripapillary part 1 day after surgery and recovered after 1 week. ΔACD and ΔLT showed no significant correlation 1 day after surgery. ΔACD was negatively correlated with ΔLT and sphere 1 week after surgery (r = − 0.847, p < 0.000; r = − 0.398, p = 0.002). ΔLT was positively correlated with the sphere 1 week after surgery (r = 0.256, p = 0.048). Conclusion The anterior segment was the most affected, while the retina also underwent changes with regard to MT, RNFL, CT, macular vessel density, and peripapillary vessel density.

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Section: Discussionmentioning

confidence: 99%

Short-term changes in the anterior segment and retina after small incision lenticule extraction

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Vessel density changes were assumed by the suction effects during surgery on retinal microcirculation, and instantaneous changes of suction may cause ischemia-reperfusion injury [9]. IOP Elevation during surgery also caused a decrease in ocular blood ow [24]. In a paper studied healthy people by increasing IOP, researchers found transient elevation of IOP altered optic nerve head topography [25].…”

Section: Discussionmentioning

confidence: 99%

Short Term Changes in Anterior Segment and Retina After Small Incision Lenticule Extraction

Chen

Liao

Ying

et al. 2020

Preprint

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Purpose: To analyze changes of the anterior segment and retina after small incision lenticule extraction (SMILE) in the short term.Methods: Myopia patients scheduled for SMILE were recruited in Ruijin Hospital, Shanghai, China. Basic information of patients such as age, gender, and refractive errors was recorded. Ocular measurements were taken before surgery, 1 day and 1 week after surgery, including axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), white to white (WTW), pupil diameter (PD), macular thickness (MT), ganglion cell layer thickness (GCL), retinal nerve fiber layer thickness (RNFL), choroidal thickness (CT), macular vessel density, optic disc vessel density. Results of postoperative were compared to baseline, respectively, with paired student t test, and the results were considered statistically significant when p<0.05. Correlations between sphere and changes of ACD (𝜟ACD) and LT (𝜟LT) were analyzed with the Pearson correlation coefficient.Results: 61 eyes of 31 patients were selected for this study. AL, CCT, ACD, and PD postoperative were significantly reduced (p<0.05), while LT was thickened after surgery (p<0.05). MT at the fovea decreased on 1 day and 1 week after surgery (p<0.05). GCL was no statistical changes after surgery. RNFL was unchanged 1 day after surgery, but the inferior sector was thickened 1 week after surgery. CT was observed thicker at fovea 1 day after surgery and 1.0mm from the fovea in nasal 1 week after surgery. Macular vessel density was significantly decreased on 1 day after surgery and most recovered in 1 week. Optic disc vessel density decreased at the peripapillary part on 1 day after surgery and recovered in 1 week. 𝜟ACD and 𝜟LT were found no significant correlation on 1 day after surgery. 𝜟ACD was negatively correlated with 𝜟LT and sphere on 1 week after surgery (r=-0.847, p<0.000; r=-0.398, p=0.002). 𝜟LT was positively correlated with the sphere on 1 week after surgery (r=0.256, p=0.048).Conclusion: Anterior segment was the most influenced while the retina was also impacted in MT, RNFL, CT, macular vessel density, and peripapillary vessel density.

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“…Vessel density changes were assumed by the suction effects during surgery on the retinal microcirculation, and instantaneous changes in suction may cause ischaemia-reperfusion injury [11]. IOP elevation during surgery also caused a decrease in ocular blood ow [24]. In a study on healthy people by increasing IOP, researchers found that transient elevation of IOP altered optic nerve head topography [25].…”

Section: Discussionmentioning

confidence: 99%

Short-Term Changes in the Anterior Segment and Retina after Small Incision Lenticule Extraction

Chen

Liao

Ying

et al. 2020

Preprint

View full text Add to dashboard Cite

Background: To analyse short-term changes in the anterior segment and retina after small incision lenticule extraction (SMILE).Methods: Patients with myopia scheduled for SMILE were recruited from Ruijin Hospital, Shanghai, China. Basic patient information such as age, sex, and refractive errors was recorded. Ocular measurements were taken before surgery, and 1 day and 1 week after surgery; they included axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), white to white (WTW), pupil diameter (PD), macular thickness (MT), ganglion cell layer thickness (GCL), retinal nerve fiber layer thickness (RNFL), choroidal thickness (CT), macular vessel density, and optic disc vessel density.Results: Sixty-one eyes of 31 patients were selected for this study. AL, CCT, ACD, and postoperative PD were significantly reduced (p<0.05), while LT was thickened after surgery (p<0.05). MT at the fovea decreased 1 day and 1 week after surgery (p<0.05). GCL showed no significant changes after surgery. RNFL was unchanged 1 day after surgery, but the inferior sector was thickened 1 week after surgery. CT was thicker at the fovea 1 day after surgery and 1.0 mm from the fovea in the nasal sector 1 week after surgery. Macular vessel density was significantly decreased 1 day after surgery and most recovered in 1 week. Optic disc vessel density decreased at the peripapillary part 1 day after surgery and recovered after 1 week. 𝜟ACD and 𝜟LT showed no significant correlation 1 day after surgery. 𝜟ACD was negatively correlated with 𝜟LT and sphere 1 week after surgery (r=-0.847, p<0.000; r=-0.398, p=0.002). 𝜟LT was positively correlated with the sphere 1 week after surgery (r=0.256, p=0.048).Conclusion: The anterior segment was the most affected, while the retina also underwent changes with regard to MT, RNFL, CT, macular vessel density, and peripapillary vessel density.

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Changes in Retinal Vasculature and Thickness after Small Incision Lenticule Extraction with Optical Coherence Tomography Angiography

Cited by 16 publications

References 29 publications

Short-term changes in the anterior segment and retina after small incision lenticule extraction

Short-term changes in the anterior segment and retina after small incision lenticule extraction

Short Term Changes in Anterior Segment and Retina After Small Incision Lenticule Extraction

Short-Term Changes in the Anterior Segment and Retina after Small Incision Lenticule Extraction

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