“…A number of TTU derivation studies report regression-based mappings from disease-specific descriptive measures to generic utility-based measures for osteoarthritis, 16 obesity, 29 schizophrenia, 30 hydrocephalus, 31 stable angina, 32 coronary artery disease, 33 and asthma. 34 For example, Melsop and others 33 predicted TTO scores from a battery of measures (R 2 = 0.31), including the Duke Activity Status Index (DASI), self-rated health status (text continued on p. 77) Bosch and Hunink 9 Brazier and Roberts 43 Brazier and others 29 Brazier and others 42 Brazier and others 41 Bult and others 10 Clayson and others 30 Daley and others 47 Donnelly and others 56 Franks and others 23 Franks and others 24 Fryback and others 6 Fryback and others 11 Gray and others 39 Haby and others 55 Heuzenroeder and others 53 Kind and Macran 48 Kulkarni 31 Lawrence and Fleishman 25 Lenert and others 45 Lenert and others 46 …”