Changes in Preterm Breast Milk Nutrient Content in the First Month

Hsu, Ya-Chu; Chen, Chao-Huei; Lin, Ming-Chih; Tsai, Chi-Ren; Liang, Jiin-Tsae; Wang, Teh-Ming

doi:10.1016/j.pedneo.2014.03.002

Cited by 62 publications

(60 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This is consistent with the results from multiple studies (Hennart et al 1991; Molinari et al 2013; Reddy et al 1977; Sanchez-Pozo et al 1986; Shashiraj et al 2006; Trend et al 2015). Differing results were presented by Hsu et al 2014; they found a stable LF concentration in the first month in the milk from mothers from Taiwan; however, they started collecting samples 5–7 days postpartum. Van der Strate et al also found no significant difference during the course of lactation, although they highlight a 7-fold decrease in LF concentration from colostrum compared to samples from 2 weeks after birth (van der Strate et al 2001).…”

Section: Factors Affecting Lf Concentration In Breast Milkmentioning

confidence: 97%

“…Similarly, Mehta & Petrova (2011) have found that very preterm delivery was associated with higher levels of sIgA, lysozyme and adiponectin in transitional milk, but lower LF and leptin (p<0.05). Moreover, some authors have also performed studies that did not find a significant difference between preterm and term milk (Britton 1986; Hsu et al 2014; López et al 1997; Molinari et al 2013; Ronayne de Ferrer et al 2000). Broadhurst et al (2015) have published a recent study that included 30 mothers at their second and fifth week of lactation, organized in three groups according to gestational age (very premature, premature and full term), and found no significant differences.…”

Section: Factors Affecting Lf Concentration In Breast Milkmentioning

confidence: 99%

See 1 more Smart Citation

Factors affecting lactoferrin concentration in human milk: how much do we know?

Villavicencio

Rueda

Turin

et al. 2017

Biochem. Cell Biol.

View full text Add to dashboard Cite

Lactoferrin (LF) is a breast milk glycoprotein with antimicrobial and anti-inflammatory effects. Its beneficial properties in infants, especially in those born preterm, are currently being studied in clinical trials. However, the maternal and nursing infant factors that may affect the concentration of LF in breast milk are still not clear. We conducted a systematic review to investigate the factors that may affect LF concentration. We used a 2-step approach to identify the eligible studies according to inclusion/exclusion criteria and to determine which studies would be considered. We included 70 qualified articles from 29 countries with publication dates ranging from 1976 to 2015. We described the correlation between LF concentration in breast milk and lactation stage; 10 maternal factors, such as race, parity, among others; and 2 infant factors, infections and prematurity. Colostrum has the highest LF levels, but they decrease with days postpartum. No other factor has been consistently associated with LF concentration. A major limitation of the majority of the published studies is the small sample size and the different methods used to measure LF concentration. Therefore, there is a need for large, multicenter studies with standardized study design, sample collection, and LF measurement methods to identify clinically significant factors associated with LF expression in breast milk, which will help promote exclusive breastfeeding in preterm infants.

show abstract

Section: Factors Affecting Lf Concentration In Breast Milkmentioning

confidence: 97%

Section: Factors Affecting Lf Concentration In Breast Milkmentioning

confidence: 99%

Factors affecting lactoferrin concentration in human milk: how much do we know?

Villavicencio

Rueda

Turin

et al. 2017

Biochem. Cell Biol.

View full text Add to dashboard Cite

show abstract

“…Studies confirmed that colostrum contains higher concentrations of immune-protective agents compared with mature human milk, such as lactoferrin, lysozyme, and sIgA (9)(10)(11). Therefore, giving colostrum as soon as excreted from their mother can provide more immunological support for immature preterm newborns.…”

Section: Introductionmentioning

confidence: 93%

Oropharyngeal Colostrum Administration in Very Low Birth Weight Infants: A Randomized Controlled Trial*

Zhang

et al. 2017

Pediatric Critical Care Medicine

View full text Add to dashboard Cite

show abstract

“…The sIgA levels in breast milk decrease over time during the postpartum period [8]. Recent studies have identified no difference in breast milk sIgA concentration of preterm versus term breast milk [6,8], although Mehta and Petrova identified that preterm milk contains a higher concentration of sIgA in the first six to eight days of lactation [9].…”

Section: Maternal Soluble Igamentioning

confidence: 99%

A Review of the Immunomodulating Components of Maternal Breast Milk and Protection Against Necrotizing Enterocolitis

2019

View full text Add to dashboard Cite

Breast milk contains immunomodulating components that are beneficial to newborns during maturation of their immune system. Human breast milk composition is influenced by an infant’s gestational and chronological age, lactation stage, and the mother and infant’s health status. Major immunologic components in human milk, such as secretory immunoglobulin A (IgA) and growth factors, have a known role in regulating gut barrier integrity and microbial colonization, which therefore protect against the development of a life-threatening gastrointestinal illness affecting newborn infants called necrotizing enterocolitis (NEC). Breast milk is a known protective factor in the prevention of NEC when compared with feeding with commercial formula. Breast milk supplements infants with human milk oligosaccharides, leukocytes, cytokines, nitric oxide, and growth factors that attenuate inflammatory responses and provide immunological defenses to reduce the incidence of NEC. This article aims to review the variety of immunomodulating components in breast milk that protect the infant from the development of NEC.

show abstract

Changes in Preterm Breast Milk Nutrient Content in the First Month

Cited by 62 publications

References 25 publications

Factors affecting lactoferrin concentration in human milk: how much do we know?

Factors affecting lactoferrin concentration in human milk: how much do we know?

Oropharyngeal Colostrum Administration in Very Low Birth Weight Infants: A Randomized Controlled Trial*

A Review of the Immunomodulating Components of Maternal Breast Milk and Protection Against Necrotizing Enterocolitis

Contact Info

Product

Resources

About