Changes in postprandial gut hormones after metabolic surgery: a comparison of gastric bypass and sleeve gastrectomy

Lee, Wei Jei; Chen, Chih-Yen; Chong, Keong; Lee, Yi Chih; Chen, Shu Chun; Lee, Shou Dong

doi:10.1016/j.soard.2011.07.009

Cited by 148 publications

(102 citation statements)

References 30 publications

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“…Findings by a number of researchers support our result that different bariatric procedures have a similar effect in type 2 diabetes mellitus remission [9,11,[25][26][27][28][29]. Contrastingly, other studies show improved type 2 diabetes mellitus remission in patients who underwent gastric bypass compared to patients who underwent other surgical techniques [30,31]. Nonetheless, these articles focus on non-obese or nonmorbidly obese patients, whilst the patients described in our work, as well as other works with comparable results, were morbidly obese, which could influence the outcome of different bariatric surgery procedures in type 2 diabetes mellitus remission.…”

Section: Discussionsupporting

confidence: 87%

Remisja cukrzycy typu 2 po leczeniu bariatrycznym — porównanie różnych procedur

Fernández-Soto¹,

Martín-Leyva²,

González-Jiménez³

et al. 2017

Endokrynologia Polska

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Introduction: We aimed to assess the mid-term type 2 diabetes mellitus recovery patterns in morbidly obese patients by comparing some relevant physiological parameters of patients of bariatric surgery between two types of surgical procedures: mixed (roux-en-Y gastric bypass and biliopancreatic diversion) and restrictive (sleeve gastrectomy). Material and methods: This is a prospective and observational study of co-morbid, type 2 diabetes mellitus evolution in 49 morbidly obese patients: 37 underwent mixed surgery procedures and 12 a restrictive surgery procedure. We recorded weight, height, body mass index, and glycaemic, lipid, and nutritional blood parameters, prior to procedure, as well as six and twelve months post-operatively. In addition, we tested for differences in patient recovery and investigated predictive factors in diabetes remission. Results: Both glycaemic and lipid profiles diminished significantly to healthy levels by 6 and 12 months post intervention. Type 2 diabetes mellitus showed remission in more than 80% of patients of both types of surgical procedures, with no difference between them. Baseline body mass index, glycated haemoglobin, and insulin intake, among others, were shown to be valuable predictors of diabetes remission one year after the intervention. Conclusions:The choice of the type of surgical procedure did not significantly affect the remission rate of type 2 diabetes mellitus in morbidly obese patients. (Endokrynol Pol 2017; 68 (1): 18-25)

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Section: Discussionsupporting

confidence: 87%

Remisja cukrzycy typu 2 po leczeniu bariatrycznym — porównanie różnych procedur

Fernández-Soto¹,

Martín-Leyva²,

González-Jiménez³

et al. 2017

Endokrynologia Polska

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“…14 Metabolic effects are attributed primarily to reduced production of ghrelin. 15 This hormone is mainly secreted by X/A-like cells in the oxyntic glands in the gastric fundus, which is resected during an LSG. Ghrelin is orexigenic.…”

Section: Discussionmentioning

confidence: 99%

Laparoscopic sleeve gastrectomy: perioperative outcomes, weight loss and impact on type 2 diabetes mellitus over 2 years

Hoogerboord

Wiebe

Klassen

et al. 2014

cjs

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“…The initial search identified 581 publications, of which 576 were excluded, leaving 5 publications for analysis. [14][15][16][17][18] One study, 19 which was the subset of another study, 14 was excluded; another study 20 was the republication of the trial by Woelnerhanssen and colleagues 15 and was also excluded. The 5 trials of LRYGB and LSG for morbid obesity or T2DM with a total of 396 patients that we included in our analysis were retrieved from the electronic databases.…”

Section: Discussionmentioning

confidence: 99%

Comparison of laparoscopic Roux-en-Y gastric bypass with laparoscopic sleeve gastrectomy for morbid obesity or type 2 diabetes mellitus: a meta-analysis of randomized controlled trials

Lai

et al. 2013

CJS

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Comparison of laparoscopic Roux-en-Y gastric bypass with laparoscopic sleeve gastrectomy for morbid obesity or type 2 diabetes mellitus: a meta-analysis of randomized controlled trials Background: Laparoscopic Roux-en-Y gastric bypass (LRYGB) is one of the most widely used bariatric procedures, and laparoscopic sleeve gastrectomy (LSG) as a single-stage procedure for treating morbid obesity is becoming more popular. We compared both techniques to evaluate their efficacy in treating morbid obesity or type 2 diabetes mellitus (T2DM). Methods:We searched the Cochrane Controlled Trials Register databases, Medline, Embase, ISI databases and the Chinese Biomedical Literature Database to identify randomized controlled trials (RCTs) of LRYGB and LSG for morbid obesity or T2DM published in any language. Statistical analyses were carried out using RevMan software.Results: Five worldwide RCTs with 196 patients in the LRYGB group and 200 in the LSG group were included in our analysis. Compared with patients who had LSG, those who had LRYGB had a higher remission rate of T2MD, lost more weight and had lower low-density lipoprotein, triglycerides, homeostasis model assessment index and insulin levels. There was no difference in the reoperation rate between the groups. However, patients treated with LRYGB had a higher incidence of complication than those treated with LSG. Conclusion:Our meta-analysis demonstrates that LRYGB is more effective than LSG for the surgical treatment of T2DM and control of metabolic syndrome. However, LSG is safer and has a reduced rate of complications. Further high-quality RCTs with long follow-up periods are needed to provide more reliable evidence.Contexte : La dérivation gastrique laparoscopique Roux-en-Y (DGRY) est l'une des interventions bariatriques les plus utilisées, et la gastrectomie longitudinale laparoscopique (GLL) gagne en popularité comme intervention en une seule étape pour le traitement de l'obésité morbide. Nous avons comparé les 2 techniques pour en évaluer l'efficacité dans le traitement de l'obésité morbide ou du diabète de type 2 (DT2).

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Changes in postprandial gut hormones after metabolic surgery: a comparison of gastric bypass and sleeve gastrectomy

Cited by 148 publications

References 30 publications

Remisja cukrzycy typu 2 po leczeniu bariatrycznym — porównanie różnych procedur

Remisja cukrzycy typu 2 po leczeniu bariatrycznym — porównanie różnych procedur

Laparoscopic sleeve gastrectomy: perioperative outcomes, weight loss and impact on type 2 diabetes mellitus over 2 years

Comparison of laparoscopic Roux-en-Y gastric bypass with laparoscopic sleeve gastrectomy for morbid obesity or type 2 diabetes mellitus: a meta-analysis of randomized controlled trials

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