2011
DOI: 10.1007/s00268-011-1165-9
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Changes in Metabolic Profile and Adipoinsular Axis in Morbidly Obese Premenopausal Females Treated with Restrictive Bariatric Surgery

Abstract: The results of this study suggest that weight loss through restrictive bariatric surgery results in a significant reduction in leptin, resistin, and IL-6 levels, and an increase in adiponectin levels, in addition to improving insulin sensitivity and glucose and lipid homeostasis in young morbidly obese female patients. These changes were significantly correlated with the magnitude of weight loss.

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Cited by 46 publications
(37 citation statements)
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“…In the current study, we found that weight loss after LSG was associated with a substantial decrease in resistin serum levels. The evidence on resistin response to bariatric surgery has been inconclusive; some studies reported significant reductions in serum resistin levels after bariatric surgery, while others negated this finding . Adding to the confusion, we found no significant correlation between BMI and serum resistin levels.…”
Section: Discussioncontrasting
confidence: 83%
“…In the current study, we found that weight loss after LSG was associated with a substantial decrease in resistin serum levels. The evidence on resistin response to bariatric surgery has been inconclusive; some studies reported significant reductions in serum resistin levels after bariatric surgery, while others negated this finding . Adding to the confusion, we found no significant correlation between BMI and serum resistin levels.…”
Section: Discussioncontrasting
confidence: 83%
“…Some studies found that plasma resistin levels were significantly decreased 12 months after bariatric surgery with>10% loss of the excess body weight (Edwards et al, 2010; Jankiewicz-Wika et al, 2011; Marantos et al, 2011). These studies also reported that plasma resistin levels were positively correlated with insulin resistance and glucose intolerance (Moschen et al, 2009; De Luis et al, 2010; Jankiewicz-Wika et al, 2011; Marantos et al, 2011). Other studies showed no difference in plasma resistin levels after significant weight loss caused by bariatric surgery (Wolfe et al, 2004; Iqbal et al, 2005).…”
Section: The Changes Of Novel Adipokines After Bariatric Surgery and mentioning
confidence: 99%
“…Diverse studies have shown a significant reduction in cardiovascular risk, with increased high-density lipoprotein (HDL) cholesterol and decreased triglycerides after 1 year [7,20]. As with glucose homeostasis, there is also a lack of long-term results describing changes in the lipid profile.…”
Section: Effect Of Laparoscopic Sleeve Gastrectomy On Lipid Profilementioning
confidence: 95%