Changes in Magnetic Field Maps at QRS-Onset After Myocardial Infarction

Hailer, Birgit; Leeuwen, Pim van; Donker, Dirk W.; Rahn, N.; Lange, Sebastian; Wehr, M

doi:10.1007/978-1-4612-1260-7_114

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“…Apart from using the angle of the MFM for discriminating patients with CAD, other measures have been developed and examined. These include estimations of signal strength (Chen et al 2004, Park et al 2005, Steinberg et al 2005, Lim et al 2007, the distance between MFM minimum and maximum (Hailer et al 2000, Park et al 2005, Steinberg et al 2005, Lim et al 2007 and signal amplitude (Hänninen et al 2001, Chen et al 2004. Many of these measures have also been examined with respect to iso-integral values as well as their changes over time.…”

Section: Discussionmentioning

confidence: 99%

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Ryazhskaya

2006

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We compared the stability and discriminatory power of different methods of determining cardiac magnetic field map (MFM) orientation within the context of coronary artery disease (CAD). In 27 healthy subjects and 24 CAD patients, multichannel magnetocardiograms were registered at rest. MFM orientation was determined during QT interval using: (a) locations of the positive and negative centres-of-gravity, (b) locations of the field extrema and (c) the direction of the maximum field gradient. Deviation from normal orientation quantified the ability of each approach to discriminate between healthy and CAD subjects. Although the course of orientation was similar for all methods, receiver operating characteristic analysis showed the best discrimination of CAD patients for the centre-of-gravity approach (area-under-the-curve = 86%), followed by the gradient (84%) and extrema (76%) methods. Consideration of methodological and discriminatory advantages with respect to noninvasive diagnosis of CAD suggests that the centres-of-gravity method is the most suited one.

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Section: Discussionmentioning

confidence: 99%

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Ryazhskaya

2006

PHYS-USP

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Changes in Magnetic Field Maps at QRS-Onset After Myocardial Infarction

Cited by 1 publication

References 3 publications

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