Changes in lung function in European adults born between 1884 and 1996 and implications for the diagnosis of lung disease: a cross-sectional analysis of ten population-based studies

Allinson, James P.; Afzal, Shoaib; Çolak, Yunus; Jarvis, Debbie; Bäckman, Helena; Berge, Maarten van den; Boezen, H. Marike; Breyer, Marie-Kathrin; Breyer‐Kohansal, Robab; Brusselle, Guy; Burghuber, Otto Chris; Faner, Rosa; Hartl, Sylvia; Lahousse, Lies; Lundbäck, Bo; Nwaru, Bright I.; Rönmark, Eva; Vikjord, Sigrid Anna Aalberg; Vonk, Judith M.; Wijnant, Sara R A; Lange, Peter; Nordestgaard, Børge G.; Olvera, Núria; Agustí, Àlvar; Donaldson, Gavin C.; Wedzicha, Jadwiga A.; Vestbo, Jørgen; Vanfleteren, Lowie E.G.W.

doi:10.1016/s2213-2600(21)00313-1

Cited by 19 publications

(11 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…While we cannot exclude the presence of some cohort effects in subjects born after 1935, it is also possible that the increase in lung function has indeed slowed in more recent years. This has also been suggested previously [ 11 ], where the authors, despite estimating homogeneous lung function changes with year of birth, observed that the increase appeared smaller among more recent birth cohorts. Moreover, they suggested that the cohort effects evidenced could lead one to progressively underestimate normal European lung function measured with GLI-2012 equations.…”

Section: Discussionsupporting

confidence: 86%

“…The presence of cohort effects in lung function has been reported previously. Xu et al showed a height-independent increase of FEV 1 and FVC with year of birth, analyzing data from ten cross-sectional European population-based studies of subjects born between 1884 and 1996 [11].…”

Section: Discussionmentioning

confidence: 99%

“…Secular trends in spirometric data during the 20 th century have been described previously in different populations [8][9][10][11][12], however most of the studies explored only cohort and not period effects.…”

Section: Introductionmentioning

confidence: 97%

See 2 more Smart Citations

Period and cohort effects: consequences on spirometric lung function in Norway during the 20th century

Cestelli

Johannessen²,

Stavem³

et al. 2022

ERJ Open Res

View full text Add to dashboard Cite

Background and AimSeveral factors can influence measured lung function over time. The aim of this study was to investigate period and cohort effects on spirometric measures in a large general population sample in Norway during the 20th century, using GLI-2012 equations as a reference.Methods36 466 subjects (born 1894–1969) from four cross-sectional surveys conducted between 1965 and 1999 were included, with harmonised data on smoking habits, respiratory symptoms, lung diseases, education, and spirometry. Changes in FEV1 and FVC z-scores in healthy subjects across surveys were explored to investigate period effects. Linear mixed-effects models of FEV1 and FVC z-scores on birth cohort, with survey as random effect, were used to investigate cohort effects, both in subjects of the total population and in healthy ones.ResultsRelatively higher FEV1 and FVC z-scores in healthy subjects were found in the first survey (1965–1970) compared to the more recent ones (1988–1999), suggesting period effects. FEV1 and FVC z-scores increased significantly with birth cohort from 1894 to 1935, after adjustment for covariates. A more stable trend of FEV1 and FVC z-scores with birth cohort was evidenced for subjects born more recently (1945–1969).ConclusionsAn increase of lung function with year of birth was observed in Norwegian subjects during the first half of the 20th century. The impact of period effects on lung function decreased from 1965 to 1999.

show abstract

Section: Discussionsupporting

confidence: 86%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Period and cohort effects: consequences on spirometric lung function in Norway during the 20th century

Cestelli

Johannessen²,

Stavem³

et al. 2022

ERJ Open Res

View full text Add to dashboard Cite

show abstract

“…That study entry was between 1986 and 2001 from five different cohorts can be another potential weakness as treatment guidelines changed during the recruitment period. A cohort effect of successively improved lung function in the general population may be present as large-scale studies have presented such evidence [ 43 ]. In order to account for this, the regression analyses were adjusted for original cohorts.…”

Section: Discussionmentioning

confidence: 99%

Body mass index increase: a risk factor for forced expiratory volume in 1 s decline for overweight and obese adults with asthma

et al. 2022

Self Cite

View full text Add to dashboard Cite

Background: With increasing prevalence of overweight and obesity, it is important to study how BMI change may affect lung function among subjects with asthma. There are few prospective studies on this topic, especially with separate analyses of those with normal and high BMI.Aim: To prospectively study the association between annual BMI change and annual lung function decline, separately among those with normal initial BMI and overweight/obesity, in an adult asthma cohort.Methods: A population-based adult asthma cohort was examined at study entry between 1986–2001 and at follow-up between 2012–2014 (n=945). Annual BMI change was analysed in association to annual decline in FEV1, FVC and FEV1/FVC separately in those with normal weight (BMI=18.5–24.9) and overweight/obesity (BMI≥25) at study entry. Regression models were used to adjust for sex, age, smoking, ICS use and occupational exposure to gas, dust, or fumes.Results: Subjects with overweight/obesity had lower FEV1 and FVC but slower annual FEV1 and FVC decline compared to those with normal weight. After adjustment through regression modelling, the association between BMI change with FEV1 and FVC decline remained significant for both BMI groups, but with stronger associations among the overweight/obese (FEV1 B[Overweight/obese]=−25 ml versus B[normal weight]=−15 ml). However, when including only those with BMI increase during follow-up, the associations remained significant among those with overweight/obesity, but not in the normal weight group. No associations were seen for FEV1/FVC.Conclusions: BMI increase is associated with faster FEV1 and FVC decline among overweight and obese adults with asthma in comparison with their normal weight counterparts.

show abstract

“…In this study, children were enrolled from 1974 to 1988 and observed from 1994 to 2008. As both lung function and height are increasing with the times in the world, 51 in Japanese school children the average height also increased by 5 cm (2 inches) between 1974 and 2004. 52 Our cohort program did not assess total lung capacity and functional residual capacity.…”

Section: Dovepressmentioning

confidence: 99%

Poor Asthma Control in Schoolchildren May Lead to Lower Lung Function Trajectory from Childhood to Early Adulthood: A Japanese Cohort Study

Tsuneyoshi¹,

Kawayama²,

Sasaki³

et al. 2022

JAA

View full text Add to dashboard Cite

Purpose Although childhood asthma is a risk factor for adult lung function disorders, the correlation between childhood asthma control level and lung function growth remains unclear in Japan. The correlation between childhood asthma control and early adulthood lung function growth was investigated in this study. Patients and Methods We included 505 children with asthma from the Omuta City Air Pollution-Related Health Damage Cohort Program. The characteristics and lung function of girls and boys aged 6–11 years and 12–17 years were compared between poor and good asthma control groups. Results Among the 505 children, 214 (42.4%) showed poor asthma control. The mean percentage forced expiratory volume in 1 second predicted for girls and boys aged 6–11 years (80.2% and 79.2%, respectively) and 12–17 years (80.0% and 81.1%, respectively) in the poor control group was significantly lower than those of girls and boys aged 6–11 years (87.9% and 87.3%, respectively) and 12–17 years (88.1% and 87.8%, respectively) in the good control group. However, a linear regression model did not reveal between-group differences in the slopes of lung function growth for both sexes. Girls (24.6%, P < 0.0001) and boys (24.4%, P = 0.0026) in the poor control group had a significantly higher proportion of young adults with obstructive ventilatory patterns than girls (1.4%) and boys (8.1%) in the good control group. Conclusion Our findings revealed that poor childhood asthma control leaded to lung function disorders, which suggest the importance of early asthma control in school children.

show abstract

Changes in lung function in European adults born between 1884 and 1996 and implications for the diagnosis of lung disease: a cross-sectional analysis of ten population-based studies

Cited by 19 publications

References 29 publications

Period and cohort effects: consequences on spirometric lung function in Norway during the 20th century

Period and cohort effects: consequences on spirometric lung function in Norway during the 20th century

Body mass index increase: a risk factor for forced expiratory volume in 1 s decline for overweight and obese adults with asthma

Poor Asthma Control in Schoolchildren May Lead to Lower Lung Function Trajectory from Childhood to Early Adulthood: A Japanese Cohort Study

Contact Info

Product

Resources

About