Changes in lipid profile of patients referred to a cardiac rehabilitation program

Sarrafzadegan, Nizal; Rabiei, Katayoun; Kabir, Ali; Asgary, S.; Tavassoli, Aliakbar; Khosravi, Alireza; Chalian, Hamid

doi:10.1097/hjr.0b013e328300271f

Cited by 19 publications

(19 citation statements)

References 35 publications

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“…Yusuf et al [29] showed that for an LDL cholesterol reduction of 1 mmol/l (38.7 mg/dl) there is a 21% reduction in cardiovascular events. Our patients experienced a 22% decrease in LDL levels after exercise training, a slightly larger improvement than what was found in other studies [9,30] . This positive effect of exercise was seen on top of statin therapy, which most patients were already taking at the beginning of the program (and that did not change significantly during phase II).…”

Section: Discussioncontrasting

confidence: 50%

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Cardiac Rehabilitation after an Acute Coronary Syndrome: The Impact in Elderly Patients

et al. 2015

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Introduction: Cardiac rehabilitation (CR) has been shown to decrease mortality and morbidity, improve the control of risk factors and the quality of life of patients with coronary artery disease. However, the elderly are underrepresented in most studies and in real-life CR programs. Our goal was to evaluate the impact of CR after an acute coronary syndrome in the elderly population. Methods: A cutoff of 65 years was used to dichotomize age. Our main focus was on the effects of ambulatory supervised exercise training on several surrogate markers, namely total cholesterol, low- and high-density lipoprotein cholesterol, triglycerides, body mass index, fasting glucose, glycated hemoglobin, probrain natriuretic peptide, International Physical Activity Questionnaire score, maximal exercise capacity, chronotropic response index and heart rate recovery. We evaluated those variables at the beginning and at the end of phase II of the CR program (after 3 months) and repeated the treadmill test at 12 months. Results: A total of 548 patients with a recent acute coronary syndrome were enrolled; 37% were 65 years old or older. Both age groups had a statistically significant improvement in all the evaluated parameters. Interestingly, at 12 months both groups maintained the improvement in functional capacity seen immediately after 3 months. Conclusions: The benefits of CR in terms of functional capacity, metabolic profile and other prognostic parameters were significant in both younger and older patients. Therefore, all eligible patients should be referred to CR programs, irrespective of age.

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Section: Discussioncontrasting

confidence: 50%

“…It has also been shown to improve the metabolic profile and control of risk factors, the quality of life and the functional capacity of these patients [9] . However, CR is still underutilized, across all Europe, and particularly in Portugal [10] .…”

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confidence: 99%

Cardiac Rehabilitation after an Acute Coronary Syndrome: The Impact in Elderly Patients

et al. 2015

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“…Cardiac rehabilitation provides a substantial benefit in management of major CV risk factors including lipid profile and BP in patients with CV diseases 36. The 3- to 4-week inpatient cardiac rehabilitation in Germany is designed according to the recommendations of national and European Society of Cardiology guidelines37 and offers the opportunity not only to monitor patients after ACS but also to reinforce secondary preventive approaches in the long-term treatment of CAD.…”

Section: Discussionmentioning

confidence: 99%

Disparity in risk factor pattern in premature versus late-onset coronary artery disease: a survey of 15,381 patients

Reibis¹,

Treszl²,

Wegscheider³

et al. 2012

VHRM

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BackgroundThere are few data available regarding the specificity and modifiability of major cardiovascular (CV) risk factors in patients with premature versus (vs) late-onset coronary artery disease (CAD). This study was designed to analyze and compare these risk factors.Patients and methodsData from 15,381 consecutive patients (mean age, 62.3 ± 11.7 years; female, 33.8%) hospitalized with CAD were collected from a large-scale registry (Transparency Registry to Objectify Guideline-Oriented Risk Factor Management) and analyzed. The patients were divided into two groups, depending on age at inclusion: group 1 patients (n = 5725; mean age, 50.5 ± 7.2 years) were males aged < 55 years and females aged < 65 years; group 2 patients (n = 9656; mean age, 69.4 ± 7.4 years) were males aged > 55 years and females aged > 65 years and had a low-density lipoprotein cholesterol level of >100 mg/dL on admission to cardiac rehabilitation. Besides the conventional risk factors, lipoprotein(a) concentrations and glucose tolerance were measured facultatively. Univariate (chi-square test) and multivariate logistic regression models were used.ResultsCigarette smoking (group 1 at 31.5% vs group 2 at 9.4%; P < 0.001), family history of CAD (group 1 at 43.6% vs group 2 at 26.5%; P < 0.001), and dyslipidemia (group 1 at 92.7% vs group 2 at 91.8%; P < 0.001) were dominant risk factors in the younger group. Arterial hypertension (group 1 at 71.4% vs group 2 at 87.0%; P < 0.001) and diabetes (group 1 at 23.5% vs group 2 at 30.1%; P < 0.001) were dominant risk factors in the older group. Impaired glucose tolerance and diabetes were less frequent in the younger group (Ptrend = 0.038), and identical lipoprotein(a) concentration levels of >30 mg/dL were found in both groups (8.0%; P = 0.810). Modification of lipid profile and blood pressure was more effective in the younger group (low-density lipoprotein cholesterol < 100 mg/dL: group 1 at 66.3% vs group 2 at 61.1%; systolic blood pressure < 140 mmHg: group 1 at 91.7% vs group 2 at 83.0%; P < 0.001).ConclusionCV risk factors differ markedly between premature and non-premature CAD. Cardiac rehabilitation provides an opportunity to reinforce secondary prevention after acute coronary syndrome.

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“…Inúmeros estudos vêm relatando os benefícios da reabilitação cardíaca (RC) na diminuição da morbidade e mortalidade de pacientes submetidos à cirurgia de revascularização miocárdica (CRM) e doença aterosclerótica coronariana (DAC) 1,2 . Segundo, o Serviço de Saúde Pú-blica dos EUA, a reabilitação cardíaca é definida como um programa que envolve avaliação médica, exercícios supervisionados, educação e orientação para pacientes com doenças cardíacas 3 .…”

Section: Introductionunclassified

Reabilitacao cardiaca em pacientes submetidos a cirurgia de revascularizacao do miocardio

Aikawa

Cintra

Oliveira

et al. 2014

Rev Bras Med Esporte

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INTRODUÇÃO: Os programas de reabilitação cardíaca (PRC) vêm diminuindo a morbidade e a mortalidade em pacientes após cirurgias de revascularização do miocárdio (CRM). OBJETIVO: Observar a adesão de pacientes submetidos à CRM isoladamente na fase tardia a um PRC e analisar a qualidade de vida e capacidade funcional antes e após o treinamento físico de três meses de PRC. MÉTODOS: Foram contatados todos os pacientes submetidos à CRM isoladamente no período de um ano para participarem de um PRC com duração de três meses com três sessões semanais de uma hora de duração. Todos os pacientes realizaram exames bioquímicos de sangue, teste de força muscular de uma repetição máxima (1-RM) para membros superiores e inferiores, teste de caminhada dos 6 minutos (TC6) e responderam o questionário de qualidade de vida SF-36 antes e após o treinamento. RESULTADOS: De todos os 86 pacientes contatados, apenas 13% (n = 11) concluíram o PRC. A média de idade foi 67 ± 9 anos. O sexo masculino foi predominante, 73% (oito homens). Não houve alterações significativas nos exames bioquímicos laboratoriais. No TC6 houve um aumento significativo na distância percorrida (p = 0,014); quanto à força muscular houve um aumento significativo na carga para o teste em membros superiores (p = 0,043); e no questionário SF-36 não observamos diferenças significativas nos escores antes e depois dos três meses de PRC. CONCLUSÃO: A adesão ao PRC foi baixa, logo é de suma importância a divulgação da participação de pacientes que realizaram CRM nesses programas para proporcionar maior capacidade funcional.

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Changes in lipid profile of patients referred to a cardiac rehabilitation program

Abstract: Comprehensive CRP improves TC, TG, LDL, and HDL in Iranian patients with cardiovascular disease even without antilipid drugs, and antilipid therapy can boost this effect.

Cited by 19 publications

References 35 publications

Cardiac Rehabilitation after an Acute Coronary Syndrome: The Impact in Elderly Patients

Cardiac Rehabilitation after an Acute Coronary Syndrome: The Impact in Elderly Patients

Disparity in risk factor pattern in premature versus late-onset coronary artery disease: a survey of 15,381 patients

Reabilitacao cardiaca em pacientes submetidos a cirurgia de revascularizacao do miocardio

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