Changes in Lifespan as an Integral Response to the Organism’s Immune Status and Mobile Elements Activity
M. V. Trostnikov,
D. R. Malyshev,
E. G. Pasyukova
Abstract:One of the key goals in studying the molecular and genetic basis of many pathologies is to find triggers, which could positively influence the incidence of age-dependent diseases and the rate of aging in general. A possible cause of age-dependent degradation of the organism functions inducing aging is immunosenescence. It is known that the increased activity of mobile elements observed with age may not only affect the level of genome stability, but also play a crucial role in the development of immune response… Show more
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