Changes in Levels of Serum Cytokines and Chemokines in Perforated Appendicitis in Children
Wen-Ya Lin,
En-Pei Lee,
Chun-Yu Chen
et al.
Abstract:Appendicitis is primarily diagnosed based on intraoperative or histopathological findings, and few studies have explored pre-operative markers of a perforated appendix. This study aimed to identify systemic biomarkers to predict pediatric appendicitis at various time points. The study group comprised pediatric patients with clinically suspected appendicitis between 2016 and 2019. Pre-surgical serum interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), intercellular cell-adhesion molecule-1 (ICAM-1), and e… Show more
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