Changes in left ventricular wall stress during isometric and isotonic exercise in healthy men

Heng, Ming K.; Bai, Jie; Marin, Jairo

doi:10.1016/0002-9149(88)91224-6

Cited by 23 publications

(11 citation statements)

References 20 publications

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“…Such a decrease in the systolic wall stress during ergometer exercise was also reported by Heng et al [8] and may be most appropriately explained by the asso ciated increase in the ventricular wall thickness. A slight increase in LV mass at exercise may be explained by an increase in the coronary flow and a decrease in the long axis internal dimension during exercise.…”

Section: Calculation Of Hemodynamic Indexessupporting

confidence: 78%

“…In conclusion, our data provide important information to explain the physiology of LV performance during supine ergometer exercise more clearly than previous reports [1][2][3][4][5][6][7][8] because LVID, LVED and LV wall thick ness were simultaneously measured. This method of anal ysis may provide us information about the pathophysiolo gy even in patients with heart diseases without regional wall motion abnormality.…”

Section: Discussionsupporting

confidence: 46%

“…sized hearts without segmental myocardial disease. The effects of exercise on LV function have been extensively investigated in experimental and clinical studies by using various techniques such as right heart catheterization, radionuclide angiography and echocardiography [1][2][3][4][5][6][7][8]. …”

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confidence: 99%

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Echocardiographie Determination of Stroke Volume and Ejection Fraction during Exercise: Analysis from Left Ventricular External Dimension

Kohama¹,

Masuyama²,

Nanto³

et al. 1994

Am J Noninvas Cardiol

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To examine the role of left ventricular (LV) wall thickening in the increase of ejection fraction during supine ergometer exercise, M-mode echocardiography was used to assess LV diameters and performance during staged ergometer exercise. Ergometer exercise was done in 15 healthy subjects (mean age of 25 years) using a cycle ergometer by 25 W/min increments every 3 min to exhaustion with measuring systolic blood pressure. Exercise was stopped at a mean time of 14 min. Ejection fraction significantly increased from 0.64 at rest to 0.78 at peak exercise as the stages went up. Wall thickness of the LY posterior wall (PW) and ventricular septal wall (VS) at end-systole increased significantly from 13 mm (PW) and 12 mm (VS) at rest to 16 mm (PW) and 15 mm (VS) at peak exercise. LV internal dimension (LVID) in end-systole decreased significantly from 30 mm at rest to 24 mm at peak exercise as the stages went up. LVID at end-diastole did not change from 47 mm at rest during light exercise, and slightly decreased to 46 mm at peak exercise. There was no change in LV external dimension either at end-systole or at end-diastole during any stage of exercise. Decreases in end-systolic and end-diastolic LVID during exercise resulted only from the increase in LV wall thickening. In conclusion, the increase in ejection fraction during supine ergometer exercise results mainly from an increase in end-systolic wall thickness, not from Frank-Starling effect in normal subjects.

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Section: Calculation Of Hemodynamic Indexessupporting

confidence: 78%

Section: Discussionsupporting

confidence: 46%

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Echocardiographie Determination of Stroke Volume and Ejection Fraction during Exercise: Analysis from Left Ventricular External Dimension

Kohama¹,

Masuyama²,

Nanto³

et al. 1994

Am J Noninvas Cardiol

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“…In contrast, no significant increase in HR was observed. Although isometric HG alone has been shown to have a significant impact on HR, 17 the use of dobutamine and atropine offsets this effect. In this study, the increase in ESWS that occurred with HG was small, as would be expected in subjects with normal hearts in contrast to patients with functional significant CAD.…”

Section: Discussionmentioning

confidence: 98%

Adjunctive handgrip during dobutamine stress echocardiography: Invasive assessment of myocardial oxygen consumption in humans

Khan

Otero

Font-Cordoba

et al. 2005

Clinical Cardiology

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SummaryBackground: Adjunctive isometric exercise in the form of sustained submaximal handgrip (HG) is considered to increase the sensitivity of dobutamine stress echo (DSE) for detection of functionally significant coronary artery disease.Hypothesis: The study was undertaken to quantify invasively the impact of HG in humans on hemodynamics and myocardial oxygen consumption (MVO2) during DSE.Methods: An invasive hemodynamic evaluation was performed during DSE and with addition of adjunctive HG in 11 subjects. Coronary sinus (CS) blood flow, right-sided and systemic pressures, oxygen saturations, and transthoracic two-dimensional echocardiography were obtained at each 3-min stage and after adding HG at peak DSE. Myocardial oxygen consumption was calculated by the Fick method and circumferential end-systolic wall stress (ESWS) by Mirsky's formula.Results: At peak DSE, heart rate, left ventricular ejection fraction, CS flow, and MVO2 increased, whereas pulmonary capillary wedge pressure (PCWP) and circumferential endsystolic wall stress (ESWS) decreased from baseline. Com-

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“…Other publications ratifi ed the use of the manoeuvre to produce isometric exercise and an effective postload elevation, by applying 30% to 50% of maximal force over a period of 1 to 5 minutes 18,19 . We observed that a few patients had diffi culties to maintain the same handgrip strength during the set time (fi ve minutes), and a few individuals were only able to sustain a smaller load over a shorter time, even though this has been a commonly reported problem in studies previously published regarding utilization of similar-type isometric exercises.…”

Section: E Velocity E Velocitymentioning

confidence: 99%

Análise da função diastólica do ventrículo esquerdo em hipertensos sob variação de condições hemodinâmicas provocadas: estudo comparativo entre o doppler transmitral e tissular

Danzmann¹,

Freitas²,

Araujo³

et al. 2006

Arq. Bras. Cardiol.

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OBJECTIVETo evaluate the behavior of LV diastolic displacement velocities of basal posterior septum near mitral ring segment obtained by tissue Doppler in relation to mitral fl ow velocities of hypertensive subjects, submitted to preload increase by left inferior limbs elevation for 5 minutes, and during 1 minute of handgrip (conditions 1 and 2, respectively). METHODSTwenty fi ve outpatients (15 men, 52±11 years), with arterial hypertension > 3 years, by the transmitral fl ow Doppler variables: E, A and E/A, and of tissue Doppler: E', A' and E'/A', in basal situation and in conditions 1 and 2. For comparison of results in basal situation with conditions 1 and 2 a paired t test was applied. RESULTSE(cm/s) varied from 68,88 ± 11,94 to 75,82 ± 15,71* and E'(cm/s) varied from 8,22 ± 2,30 to 8,31 ± 2,24 in condition 1 (p<0.05). In addition, a comparison of variation percent (%) of Doppler transmitral indices with corresponding tissue Doppler indices variation % showed a signifi cant difference between E and E', with preload increase (p=0.01). CONCLUSIONPatients with left ventricular adaptation to systemic arterial hypertension showed less modifi cation of the index E´ than E, after preload increase maneuver, an evidence that may suggest its more ample utilization in the context of echocardiographic left ventricular diastolic function evaluation. KEY WORDSLeft ventricular diastolic function; arterial hypertension; tissue Doppler.

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Changes in left ventricular wall stress during isometric and isotonic exercise in healthy men

Cited by 23 publications

References 20 publications

Echocardiographie Determination of Stroke Volume and Ejection Fraction during Exercise: Analysis from Left Ventricular External Dimension

Echocardiographie Determination of Stroke Volume and Ejection Fraction during Exercise: Analysis from Left Ventricular External Dimension

Adjunctive handgrip during dobutamine stress echocardiography: Invasive assessment of myocardial oxygen consumption in humans

Análise da função diastólica do ventrículo esquerdo em hipertensos sob variação de condições hemodinâmicas provocadas: estudo comparativo entre o doppler transmitral e tissular

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