Changes in L-phenylalanine concentration is a risk factor for NSCLC patients who received PD-1 Ab treatment: a case-control study
Yaqing Liu,
Yu Ping,
Liubo Zhang
et al.
Abstract:Background
Chemotherapy combined with checkpoint blockade antibodies that target programmed cell death protein (PD-1) has achieved remarkable success in non-small cell lung cancer (NSCLC). However, only a small percentage of NSCLC patients experience long-term benefits. We aimed to design and validate a clinical predictive indicator based on serum metabolism for chemotherapy in combination with PD-1 treatment.
Methods
Here, we collected serial blood samples from 49 patients with NSCLC who underwent combined … Show more
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