Changes in kidney stones type according to sex and age in Tunisian patients

Alaya, Akram; Nouri, Abdellatif; Belgith, Mohsen; Saad, H.; Hell, Iára Belink; Hellara, W.; Jouini, R.; Najjar, Mohamed Fadhel

doi:10.1016/j.acuroe.2012.04.002

Cited by 5 publications

(5 citation statements)

References 26 publications

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“…Moreover, weddellite is present in 38.5 % of the cases, the majority in 15 % of the calculi, and 12.7 % of the nuclei. These results agree with the results found in France 2,24 , Italy 16 , Israeli 25 , and Tunisia 26 . The monohydrate or whewellite form is oxalate dependent and attached to hyperoxaluria.…”

Section: Frequency Of the Constituents In The Overall Chemical Compossupporting

confidence: 92%

Morphological and crystallographic analysis of kidney stones in Eastern Morocco

guerrouj¹,

Bencheikh²,

Imtara

et al. 2020

Mediterr.J.Chem.,

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Abstract: Renal lithiasis is a common disease in the eastern region of Morocco, as it threatens the public health because of its repetitive nature as well as the complications it can cause in the kidney. Objective: This study aims to investigate the morphological, molecular, and crystallographic characteristics of kidney stones affecting patients, specifically in the eastern region of Morocco.Methods: Morphological and constitutional analyses of 239 renal lithiases made it possible to identify the various crystalline forms present, to assess the structure of the stones and to determine the composition of their nucleation zone. Results: It appears that calcium oxalate is the main component of the analyzed stones. It represents 70.5 % of the stones, which 55.5 % are majority whewellite and 15 % in weddellite. In comparison, calcium phosphates and magnesium (carbapatite and struvite) are the majority in only 8.9 % of cases, uric acid in 19.8 % of stones, and ammonium acid urate in 0.8 %. Calcium oxalate is predominant in the core of 52.5 % of the stones, carbapatite in 24.1 %, and uric acid in 20.3 % and struvite in 2.9 %. Most of the stones analyzed consist of a mixture of different crystalline constituents. Only 9.3 % of the stones analyzed have a homogeneous composition. Several types of associations were identified, the main ones being whewellite-carbapatite and whewellite-weddellite-carbapatite. Conclusion: The present study shows that calcium oxalate is the most common compound in the samples studied, followed by the uric acid compound.

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Section: Frequency Of the Constituents In The Overall Chemical Compossupporting

confidence: 92%

Morphological and crystallographic analysis of kidney stones in Eastern Morocco

guerrouj¹,

Bencheikh²,

Imtara

et al. 2020

Mediterr.J.Chem.,

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“…As reported by others [41,55,60], men submitted more stones than women and we observed male predominance for CaOx and UA stones, and female predominance for CaP stones [3,52,[61][62][63]. The predominance of oxalate stones within mixed stones (83%) and the prevalence of UA stones (54%) in "pure" kidney stones as analyzed by FTIR spectroscopy has been recently reported also in the European part of Statistical analyses of distribution (women vs men) were performed using Pearson Chi 2 comparison or * Fisher's exact test for small group.…”

Section: Discussionsupporting

confidence: 76%

“…Type III (UA) progressively increased with age from 40 and reached the highest frequency after age 60, mainly in men as reported in France, in Tunisia and USA [56,62,66]. High temperature and humidity have been reported to impact UA stone formation in Florida [7].…”

Section: Discussionmentioning

confidence: 83%

The epidemiology of kidney stones in Belgium based on Daudon’s morpho-constitutional classification: a retrospective, single-center study

Pozdzik¹,

Hamade²,

Racapé³

et al. 2022

Comptes Rendus. Chimie

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“…O nosso estudo não revelou diferenças estatisticamente significativas entre homens e mulheres ainda que revele uma tendência para que os cálculos com ácido úrico ou urato de amónio sejam mais frequentes em homens e os com fosfato de cálcio ou fosfato amónio magnésio sejam mais frequentes em mulheres. 10,14,15 A variação etária foi mais evidente e, corroborando com outros estudos, revelou que nos indivíduos com < 50 anos apresentam significativamente mais cálculos com componente cálcico e os indivíduos mais velhos apresentam uma maior proporção de cálculos com ácido úrico. A deficiência de vitamina D e a diminuição da capacidade de absorção do cálcio ingerido é mais prevalente nos idosos, o que permite uma disponibilidade de cálcio intestinal para se ligar ao oxalato e assim reduzir a sua absorção e consequentemente levar à diminuição da excreção urinária de oxalato.…”

Section: Discussionunclassified

“…A variação entre géneros e a variação etária encontram-se também descritos e bem patentes nas diversas séries internacionais. [6][7][8][9][10] Existem poucos dados relativamente à composição dos cálculos urinários na população portuguesa, existindo apenas dois estudos publicados na forma de resumo que reportam a análise de cálculos urinários de pacientes oriundos da área de referenciação de Lisboa, tornando limitada a extrapolação a nível nacional. 11,12 Este estudo tem como objectivo a caracterização da composição química dos cálculos urinários dos doentes da região do Tâmega e Sousa, sendo ainda o primeiro estudo publicado que inclui indivíduos residentes na região Norte.…”

Section: Introductionunclassified

Urinary stone composition: Gender and age variations, and evolution in the last 7 years.

Valente¹,

Castro²,

Pereira³

et al. 2017

aup

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Objectives: To evaluate urinary stone composition in our institution, its gender and age, including variations and the evolution in the last 7 years. Material and Methods: The authors reviewed all urinary stone analysis performed since January 2009 to September 2015 in our hospital – Centro Hospitalar do Tâmega e Sousa, Penafiel, Portugal. Patients were stratified by gender, age and stone composition analyzing the evolution of stone composition in different years. The stone analysis method was infrared spectroscopy. Results: From 302 valid stone analysis reports, 55,3% were female and 44,7% were male patients. Mean patient age was 51±14 years old. A total of 7 different mineral components were identified. 51,6% (n=156) of all the stones had Calcium Oxalate, 41% (n=124) had Calcium Phosphate (33% of Apatite form), 37,7% (n=114) had Uric Acid, 22,1% (n=67) had Ammonium Urate, 9,6% (n=29) had Magnesium Ammonium Phosphate, 6,3% (n=19) had Sodium Urate, and 1,3% (n=4) had Cystine in its composition. Only 30,4% of stones had a single chemical compound. Of these 56% were pure stones of Calcium Oxalate, and 31% were pure stone of Uric Acid. The most frequent mixed stone was Calcium Oxalate + Calcium Phosphate (Apatite) followed by Uric Acid + Ammonium Urate comprehending 45% and 27% of all mixed stones respectively. Related to the ethology we divided stones into 3 groups, pure non-infection, pure infection, and mixed with component of infection, and the prevalence was 37,7%, 4,3% and 57,9% respectively. The distribution between genders was similar and the highest difference was in the Ammonium Urate compound with 28% prevalence in male and 17% in women. (p=0,379) Patients after 50 years old had more prevalence of Uric Acid component accounting for 49% of their stones.(p<0,001) . Along the 7 years of study we identified a significant reduction in the prevalence of mixed stones with component of infection, gradually decreasing from 89,6% in 2009 to 27% in 2015. Conclusions: Calcium Oxalate calculus were the most prevalent, but this difference was not as important as in other studies worldwide. This study highlights the importance of the development of National and European database to report all regional stone composition variations.

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Changes in kidney stones type according to sex and age in Tunisian patients

Cited by 5 publications

References 26 publications

Morphological and crystallographic analysis of kidney stones in Eastern Morocco

Morphological and crystallographic analysis of kidney stones in Eastern Morocco

The epidemiology of kidney stones in Belgium based on Daudon’s morpho-constitutional classification: a retrospective, single-center study

Urinary stone composition: Gender and age variations, and evolution in the last 7 years.

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