Changes in hormonal and metabolic status in men of an ethnic group Komi with overweight and obesity

Осадчук, Л. В.; Gutorova, N. V.; Yu, Ludinina A; Потолицына, Н. Н.; Bojko, Evgeny R.

doi:10.14341/2071-8713-4821

Cited by 4 publications

(1 citation statement)

References 25 publications

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“…Характерное для коренных жителей Севера повышение антиатерогенной защиты организма за счет увеличения уровня ХС ЛПВП и снижения содержания ХС ЛПОНП и ХС ЛПНП наиболее сохранено у кочующих аборигенов [14,15]. У оседлых коренных жителей вследствие изменения структуры питания, гиподинамии и развития АО такая защита значительно снижается.…”

Section: Discussionunclassified

Clinical variants of the metabolic syndrome in young people living in the Khanty-Mansiysk autonomous region – Yugra

Korneeva,

Voevoda

2024

Sibirskij nauchnyj medicinskij zhurnal

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Currently the “rejuvenation” and an increase in the number of components of the metabolic syndrome (MS) determine its clinical significance in the earlier development of diabetes mellitus, cardiovascular diseases and related complications. Aim of the study was to investigate the features of the MS clinic picture in a population of young men and womenliving in the Khanty-Mansiysk autonomous region – Yugra.Material and methods. The study included 863 young people between 18 and 44 years of age, including 344 men and women with MS and 519 people in the comparison group. Studied subgroups are represented by non-indigenous men and women living in urban and rural areas, and indigenous rural residents. The analysis of MS clinical and laboratory parameters was carried out and its clinical variants in ethnic groups were identified.Results and its discussion. According to the results of the survey of young people with metabolic syndrome, it was revealed that the combination of abdominal obesity and two components of MS were most common in young people with MS (in 50.0 % men and in 55.5 % women). The study defined regression models for each MS group and threshold values for waist circumference were set, which changes in lipid and carbohydrate metabolism were predicted.Conclusions. In groups with MS, hypertriglyceridemia was determined as its most common component. The study identified the most frequent association of abdominal obesity with hyper-LDL cholesterol and hypertriglyceridemia in patients with metabolic syndrome, in ethnic groups, this combination is more common in indigenous rural men (53.3 %) and in non-indigenous urban women (54.3 %).

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Section: Discussionunclassified

Clinical variants of the metabolic syndrome in young people living in the Khanty-Mansiysk autonomous region – Yugra

Korneeva,

Voevoda

2024

Sibirskij nauchnyj medicinskij zhurnal

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Changes in Total Cholesterol and Heart Rate in Normotensive and Hypertensive Rats under Combined Influence of Cold Exposure and Hypokinesia

et al. 2020

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The Influence of Obesity and Sedentary Lifestyle on Testosterone Level and the Main Indicators of the Metabolic Status in Young Men

Осадчук

2023

Annals RAMS

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Background. It is considered an established fact that there is an adverse trend in the male reproductive potential, which has been observed in various countries over the past decades. It is assumed that it can be formed due to the influence of individual lifestyle factors, in particular, a decrease in the level of physical activity and excessive nutrition, leading to obesity. However, the effect of obesity combined with sedentary or physically active lifestyle on the reproductive hormone level and metabolic homeostasis has not been studied well. Aims the aim of the work was to study the effects of obesity combined with sedentary or active physical lifestyle on the level of reproductive hormones and the main indicators of metabolic status of young men. Methods. In young male volunteers (median age 23 years, n = 295) from the general population, anthropometry was performed, which included body height and weight, waist and hip circumference, and body mass index (BMI); and they were also asked to fill out a questionnaire containing questions about individual lifestyle. In addition, serum concentrations of follicle stimulating and luteinizing hormones, testosterone, estradiol, inhibin B and triglycerides, total cholesterol, high and low density lipoprotein cholesterol, glucose, uric acid were evaluated. Results. The most important lipid metabolism disorders observed in overweight and obesity included an increase in triglycerides, total cholesterol, low-density lipoprotein cholesterol and a decrease in high-density lipoprotein cholesterol. Overweight and obesity in men was accompanied by an increase in waist and hip circumference, a decrease in the serum level of testosterone and inhibin B reaching in obese men the testosterone values characteristic for hypogonadism. Sedentary obese men had the increased waist circumference, lower testosterone level (median 13.6 vs. 18.0 nmol/L), elevated glucose level (median 5.8 vs. 4.9 mmol/L) compared to physically active obese men or those who prefer sports or physical recreation. Conclusions. In men, obesity negatively affects the serum level of testosterone and glucose, increases the accumulation of visceral fat, but a physically active lifestyle and sports give significant advantages to obese men, as it contributes to an increase in testosterone levels and normalization of metabolic parameters.

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Changes in hormonal and metabolic status in men of an ethnic group Komi with overweight and obesity

Cited by 4 publications

References 25 publications

Clinical variants of the metabolic syndrome in young people living in the Khanty-Mansiysk autonomous region – Yugra

Clinical variants of the metabolic syndrome in young people living in the Khanty-Mansiysk autonomous region – Yugra

Changes in Total Cholesterol and Heart Rate in Normotensive and Hypertensive Rats under Combined Influence of Cold Exposure and Hypokinesia

The Influence of Obesity and Sedentary Lifestyle on Testosterone Level and the Main Indicators of the Metabolic Status in Young Men

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