Changes in haematological characteristics of a bony fish, &lt;i&gt;Tilapia guineensis &lt;/i&gt;(Bleeker, 1862), exposed to common pesticides in the Niger Delta Wetland, Nigeria

Chindah, AC; Sikoki, F.D.; Vincent-Akpu, Ijeoma Favour

doi:10.4314/gjas.v37i1.2080

Cited by 2 publications

(3 citation statements)

References 17 publications

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“…Non-target systemic physiopathological alterations from CLP exposure such as decreased hematocrit has been reported in Tilapia guineensis (Chindah et al, 2004) and Cyprinus carpio carpio (Ural, 2013). In the present study we observed a decreased hematocrit indicating that the red blood cells (RBCs) were destroyed or the production affected.…”

Section: Discussionsupporting

confidence: 54%

“…CLP induced changes in physiopathological alterations, and hematological characteristics have also been reported in Tilapia guineensis (Chindah et al, 2004) and Cyprinus carpio carpio (Ural, 2013). On a biochemical level, recent in vitro studies with Atlantic salmon hepatocyte showed perturbation of lipid metabolism as one of the main non-AChE target effects of CLP exposure (Softeland et al, 2014, Softeland et al, 2016, Olsvik et al, 2015.…”

Section: Introductionmentioning

confidence: 83%

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Dietary pesticide chlorpyrifos-methyl affects arachidonic acid metabolism including phospholipid remodeling in Atlantic salmon (Salmo salar L.)

Sanden¹,

Olsvik²,

Søfteland³

et al. 2018

Aquaculture

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The pesticide chlorpyrifos-methyl (CLP-m) has been identified in plant ingredients intended for aquaculture feed production. To investigate systemic effects of CLP-m with emphasis on lipid metabolism, post-smolt Atlantic salmon were fed in duplicate (n=2) either diets with no CLP-m (Control) or CLP-m at different concentrations (0.1, 1.0 or 8.0 mg kg-1) for a total of 67 days (Low, Medium, High). Fish in all groups almost doubled their weight during the feeding trial from 262 ± 26g (mean ± SD) to 465 ± 64g (overall mean), with no significant effects on any growth parameters. There was a significant dosedependent inhibition of plasma cholinesterase activity (BuChE) after 67 days. The CLP-m biotransformation metabolite, TCP was detected in liver and bile, with low levels of the parent compound in the organs. Spleen somatic index decreased significantly with increasing dietary CLP-m intake. Hematocrit (%) decreased linearly with increasing dietary exposure to CLP-m after 30 days of exposure, but this decrease was less at 67 days of exposure. A significantly reduced content of arachidonic acid (ARA 20:4n-6), accompanied by a significantly increased content of the saturated fatty acid, palmitic acid (PA 16:0), was observed in liver phospholipids (PLs) with increasing dietary content of CLP-m. Major effects were seen on the PL classes in liver which showed a significantly decreased absolute content, possibly indicating inhibition of PL remodeling pathways or other membrane perturbation effects from CLP-m exposure. In conclusion, this study shows that the pesticide CLP-m is a relatively potent toxicant in Atlantic salmon, especially affecting liver PLs and ARA metabolism.

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Section: Discussionsupporting

confidence: 54%

Section: Introductionmentioning

confidence: 83%

Dietary pesticide chlorpyrifos-methyl affects arachidonic acid metabolism including phospholipid remodeling in Atlantic salmon (Salmo salar L.)

Sanden¹,

Olsvik²,

Søfteland³

et al. 2018

Aquaculture

View full text Add to dashboard Cite

show abstract

“…Due to major reduction in RBC, PCV decreased. Similar to the present findings, Chindah et al [ 15 ] found a decreased value of Hct in Tilapia guineensis to varying sublethal levels of cypermethrin and chlorpyrifos. Similar observations were also reported by Köprücü et al [ 16 ], Jayaprakash and Shettu [ 17 ], and Jeyapriya et al [ 18 ].…”

Section: Discussionsupporting

confidence: 92%

Alteration of Blood Parameters and Histoarchitecture of Liver and Kidney of Silver Barb after Chronic Exposure to Quinalphos

Mostakim

Zahangir

Mishu

et al. 2015

Journal of Toxicology

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Quinalphos (QP) is commonly used for pest control in the agricultural fields surrounding freshwater reservoirs. This study was conducted to evaluate the chronic toxicity of this pesticide on blood parameters and some organs of silver barb, Barbonymus gonionotus. Fish were exposed to two sublethal concentrations, 0.47 ppm and 0.94 ppm, of QP for a period of 28 days. All the blood parameters (red blood cell, hematocrit, and hemoglobin) and blood glucose except for white blood cells decreased with increasing concentration of toxicant and become significantly lower (p < 0.05) at higher concentration when compared with control. The derived hematological indices of mean corpuscular volume, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration were equally altered compared to control. Histoarchitectural changes of liver and kidney were observed after exposure to the QP. Hypertrophy of hepatocytes, mild to severe necrosis, ruptured central vein, and vacuolation were observed in the liver of treated groups. Highly degenerated kidney tubules and hematopoietic tissue, degeneration of renal corpuscle, vacuolization, and necrosis were evident in the kidney of treated groups. In conclusion, chronic exposure to QP at sublethal concentrations induced hematological and histological alterations in silver barb and offers a simple tool to evaluate toxicity derived alterations.

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Changes in haematological characteristics of a bony fish, <i>Tilapia guineensis </i>(Bleeker, 1862), exposed to common pesticides in the Niger Delta Wetland, Nigeria

Cited by 2 publications

References 17 publications

Dietary pesticide chlorpyrifos-methyl affects arachidonic acid metabolism including phospholipid remodeling in Atlantic salmon (Salmo salar L.)

Dietary pesticide chlorpyrifos-methyl affects arachidonic acid metabolism including phospholipid remodeling in Atlantic salmon (Salmo salar L.)

Alteration of Blood Parameters and Histoarchitecture of Liver and Kidney of Silver Barb after Chronic Exposure to Quinalphos

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