Changes in Erythrocyte Sedimentation Rate, White Blood Cell Count, Liver Enzymes, and Magnesium after Gastric Bypass Surgery

Johansson, Hans-Erik; Haenni, Arvo; Zethelius, Björn

doi:10.1155/2011/273105

Cited by 12 publications

(6 citation statements)

References 42 publications

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“…The clinical literature about effects of bariatric surgery on hematopoiesis is limited. Several reports show a decrease of total WBC and neutrophil numbers 1 year after RYGB (41)(42)(43), while there is one report suggesting that WBC and neutrophil numbers decreased 30 days after VSG (44). Although we observed a decrease of WBC and neutrophil numbers in the lean mice after VSG over time, the proportion of neutrophils is persistently higher than in sham mice.…”

Section: Vsg Causes Bone Loss Through Mechanisms Independent Of G-csfcontrasting

confidence: 68%

G-CSF partially mediates effects of sleeve gastrectomy on the bone marrow niche

Li¹,

Hardij²,

Evers³

et al. 2019

Journal of Clinical Investigation

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Section: Vsg Causes Bone Loss Through Mechanisms Independent Of G-csfcontrasting

confidence: 68%

G-CSF partially mediates effects of sleeve gastrectomy on the bone marrow niche

Li¹,

Hardij²,

Evers³

et al. 2019

Journal of Clinical Investigation

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“…Common metabolic abnormalities, such as obesity and metabolic syndrome, are pro-inflammatory states that can be associated with increased ESR levels ( 21 ). Moreover, in morbidly obese patients, surgically induced weight loss is associated with a marked decrease in ESR and white blood cell count, which may indicate general inflammatory status improvements ( 22 ).…”

Section: Discussionmentioning

confidence: 99%

Comparative efficacy of three Bayesian variable selection methods in the context of weight loss in obese women

et al. 2023

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The use of high-dimensional data has expanded in many fields, including in clinical research, thus making variable selection methods increasingly important compared to traditional statistical approaches. The work aims to compare the performance of three supervised Bayesian variable selection methods to detect the most important predictors among a high-dimensional set of variables and to provide useful and practical guidelines of their use. We assessed the variable selection ability of: (1) Bayesian Kernel Machine Regression (BKMR), (2) Bayesian Semiparametric Regression (BSR), and (3) Bayesian Least Absolute Shrinkage and Selection Operator (BLASSO) regression on simulated data of different dimensions and under three scenarios with disparate predictor-response relationships and correlations among predictors. This is the first study describing when one model should be preferred over the others and when methods achieve comparable results. BKMR outperformed all other models with small synthetic datasets. BSR was strongly dependent on the choice of its own intrinsic parameter, but its performance was comparable to BKMR with large datasets. BLASSO should be preferred only when it is reasonable to hypothesise the absence of synergies between predictors and the presence of monotonous predictor-outcome relationships. Finally, we applied the models to a real case study and assessed the relationships among anthropometric, biochemical, metabolic, cardiovascular, and inflammatory variables with weight loss in 755 hospitalised obese women from the Follow Up OBese patients at AUXOlogico institute (FUOBAUXO) cohort.

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“…49 Researchers have also shown that elevated liver Mg levels may decrease ESR level in obese gastric bypass patients. 50 However, chronic kidney disease due to atherosclerosis develops cardiovascular problems. 51 Nevertheless, the results of the present study did not show the significant differences between both MgSo 4 treated groups and all control groups regarding serum level of Cr and BUN.…”

Section: Control-vr2mentioning

confidence: 99%

<p>Magnesium Sulfate Improves Some Risk Factors for Atherosclerosis in Patients Suffering from One or Two Coronary Artery Diseases: A Double-blind Clinical Trial Study</p>

Sobhani¹,

Farshidi²,

Azarkish³

et al. 2020

CPAA

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Purpose: Given the beneficial effect of MgSO 4 on the cardiovascular system, this study was designed to investigate the effect of MgSO 4 administration on suppressing some atherosclerotic risk factors in moderate coronary artery disease patients with one or two atherosclerotic vessels. Patients and Methods: In a randomized double-blind placebo-controlled clinical trial study, 64 patients with moderate coronary artery disease (55-69% stenosis) were selected according to angiography findings. Patients were divided into four groups including patients with one or two atherosclerotic vessels treated with MgSO 4 (Mg-treated-VR1, Mg-treated-VR2, respectively), placebo treated patients with one or two atherosclerotic vessels (Control-VR1, Control-VR2, respectively). The patients received either placebo or MgSO 4 supplement capsule containing 300 mg MgSO 4 for six months on a daily basis. ESR, Ca/Mg ratio, urine Mg level, serum Mg, fibrinogen, homocysteine, uric acid, Na, K, Ca, CRP, T3, T4, TSH, BUN, and Cr concentrations were measured at baseline and every three months. Results: Serum T3, Ca, K, homocysteine, CRP, and Mg concentrations were significantly improved in Mg-treated groups compared to placebo groups. Conclusion: The results of this study showed that despite the slight change in serum magnesium level, oral administration of MgSO 4 for six months could slightly reduce the serum levels of some inflammatory and vascular factors in moderate coronary artery disease patients.

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Changes in Erythrocyte Sedimentation Rate, White Blood Cell Count, Liver Enzymes, and Magnesium after Gastric Bypass Surgery

Cited by 12 publications

References 42 publications

G-CSF partially mediates effects of sleeve gastrectomy on the bone marrow niche

G-CSF partially mediates effects of sleeve gastrectomy on the bone marrow niche

Comparative efficacy of three Bayesian variable selection methods in the context of weight loss in obese women

<p>Magnesium Sulfate Improves Some Risk Factors for Atherosclerosis in Patients Suffering from One or Two Coronary Artery Diseases: A Double-blind Clinical Trial Study</p>

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