Changes in contrast enhancement of hepatocellular carcinoma and liver: effect of temporary occlusion of a hepatic vein evaluated with spiral CT.

Murata, Souichirou; Itai, Y; Satake, Mitsuo; Asato, Masaya; Kobayashi, H; Eguchi, Naoto; Moriyama, Noriyuki

doi:10.1148/radiology.202.3.9051023

Cited by 21 publications

(9 citation statements)

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“…19 AP shunts are reported to develop due to an interruption in the portal blood flow and arterial compensation. [20][21][22] In our case, portal vein tumor thrombus interrupted the right portal venous blood flow, which might increase the arterial blood flow and help to form the AP shunts. The shunts could also steal the blood supply from the tumor, which might also be one of the possible caused of the observed tumor regression.…”

Section: Discussionmentioning

confidence: 66%

Spontaneous Regression of a Large Hepatocellular Carcinoma with Portal Vein Tumor Thrombi: Report of a Case

et al. 2000

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A 65-year-old man with chronic hepatitis C showed a markedly elevated serum alpha-fetoprotein concentration. Computed tomography revealed a huge tumor occupying the entire right hepatic lobe. Three months later, the tumor regressed spontaneously from 12 cm to 7 cm in diameter without any medical treatment. A right hepatic lobectomy was performed 4 months after the initial diagnosis. The main tumor, located in the posterior inferior segment, was completely necrotic, and had a thick fibrous capsule. Many inflammatory cells had also infiltrated into the tumor. Only a small portion of a tumor thrombus in the portal vein and one of three intrahepatic metastases contained viable cancer cells. The tumor was found to be poorly differentiated hepatocellular carcinoma. Tumor regression may have been caused by a disturbance in hepatic circulation associated with the portal vein thrombus.

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Section: Discussionmentioning

confidence: 66%

Spontaneous Regression of a Large Hepatocellular Carcinoma with Portal Vein Tumor Thrombi: Report of a Case

et al. 2000

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“…The effectiveness of such therapy depends on the idea that during hepatic venous occlusion, the portal vein becomes a draining vein, and the occluded area is supplied with hepatic arterial flow alone, which can compensatorily increase. However, this idea was derived mainly from studies (1)(2)(3)(4) in which angiography and CT arteriography were performed by using contrast material.…”

Section: Discussionmentioning

confidence: 99%

Altered Hepatic Hemodynamics Caused by Temporary Occlusion of the Right Hepatic Vein: Evaluation with Doppler US in 14 Patients

et al. 2001

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“…Similarly, hepatic venous congestion may occur in segments 6 and 7 of the right lobe graft because of the ligation or anastomotic stenosis of the right inferior accessory hepatic vein (35,37). Several studies have been performed to evaluate hemodynamic alteration after hepatic venous occlusion (38)(39)(40)(41). However, little is known today about branching patterns of the MHV and their volumetric effect on venous drainage territories with respect to right liver grafting.…”

Section: Drainage Territories Of the Middle Hepatic Veinmentioning

confidence: 99%

Branching Patterns and Drainage Territories of the Middle Hepatic Vein in Computer-Simulated Right Living-Donor Hepatectomies

Neumann

Thorn

Fischer

et al. 2006

American Journal of Transplantation

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Full right hepatic grafts are most frequently used for adult-to-adult living donor liver transplantation (LDLT).One of the major problems is venous drainage of segments 5 and 8. Thus, this study was designed to provide information on venous drainage of right liver lobes for operation-planning. Fifty-six CT data sets from routine clinical imaging were evaluated retrospectively using a liver operation-planning system. We defined and analyzed venous drainage segments and the impact of anatomic variations of the middle hepatic vein (MHV) on venous outflow from segments 5 and 8. MHV variations led to significant shifts of segment 5 drainage between the middle and right hepatic vein. In cases with the most frequent MHV branching pattern (n = 33), a virtual hepatectomy closely right to the MHV intersected drainage vessels that provided drainage for 30% of the potential graft, not taking into account potential veno-venous shunts. In individuals with inferior MHV branches that extend far into segments 5 and 6 (n = 10), the overall graft volume at risk of impaired venous drainage increased by 5% (p < 0.001). If this is confirmed in clinical trials and correlated with intraoperative findings, the use of liver operation-planning systems would be beneficial to improve overall outcome after right lobe LDLT.

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Changes in contrast enhancement of hepatocellular carcinoma and liver: effect of temporary occlusion of a hepatic vein evaluated with spiral CT.

Abstract: Hepatic vein occlusion resulted in reciprocal hemodynamic changes in the liver parenchyma relative to HCCs: Enhancement of the liver increases and that of HCCs decreases.

Cited by 21 publications

References 0 publications

Spontaneous Regression of a Large Hepatocellular Carcinoma with Portal Vein Tumor Thrombi: Report of a Case

Spontaneous Regression of a Large Hepatocellular Carcinoma with Portal Vein Tumor Thrombi: Report of a Case

Altered Hepatic Hemodynamics Caused by Temporary Occlusion of the Right Hepatic Vein: Evaluation with Doppler US in 14 Patients

Branching Patterns and Drainage Territories of the Middle Hepatic Vein in Computer-Simulated Right Living-Donor Hepatectomies

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