Changes in common melanocytic naevi after intense sun exposure: digital dermoscopic study with a 1-year follow-up

Dobrosavljevic, Danijela; Brašanac, Dimitrije; Apostolovic, Milica; Medenica, Ljiljana

doi:10.1111/j.1365-2230.2008.03064.x

Cited by 16 publications

(14 citation statements)

References 22 publications

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“…Dermoscopic pattern changes in pigmented lesions have been studied in acral lesions (8), slow-growing malignant melanoma (9), and in common melanocytic naevi after intense sun exposure (10). Articles dealing with variation in the dermoscopic pattern of congenital melanocytic naevi were published in 2006 (11) and 2007 (12).…”

Section: Discussionmentioning

confidence: 99%

Dermoscopic Changes in Melanocytic Naevi in Children during Digital Follow-up

Fortina¹,

Zattra²,

Bernardini³

et al. 2012

Acta Derm Venerol

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The aim of this study was to investigate the dermoscopic changes in acquired melanocytic naevi in a large paediatric population over an interval of several years. Images of 717 melanocytic naevi were obtained from 160 consecutive patients. Dermoscopic pigment pattern changes were observed in one of two lesions after a follow-up of one year, in 34 of 295 lesions (11.5%) after 2 years, in 40 of 190 lesions (21.1%) after 3 years, in 40 of 141 lesions (28.4%) after 4 years, in 5 of 37 lesions (13.5%) after 5 years, in 12 of 31 lesions (38.8%) after 6 years, and in 7 of 21 lesions (33.3%) after 7 years. Dermoscopic changes were detected in 25.3% of the lesions in patients aged 3-6 years, in 21% of the lesions in patients aged 7-12 years, and in 15.5% of the lesions in patients over 13 years. Main pattern changes consisted of transition from globular to globular-reticular (35 naevi), from globular to reticular (14 naevi) and from globular-reticular to reticular (24 naevi). These results are consistent with the view that melanocytic naevi generally undergo a characteristic transition from a globular pattern to a reticular pattern. Most of the changes are observed in the 3-6 years age group when hormonal and/or environmental factors are not thought to play a role in pattern alterations.

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Section: Discussionmentioning

confidence: 99%

Dermoscopic Changes in Melanocytic Naevi in Children during Digital Follow-up

Fortina¹,

Zattra²,

Bernardini³

et al. 2012

Acta Derm Venerol

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“…The main benefit of dermoscopy is the initial diagnosis of melanoma, which may not be noticed in the clinical examination because in some cases, such as melanoma in situ (limited to the most superficial skin layer), it presents a regular and homogeneous color. (3,5,6).…”

Section: Introductionmentioning

confidence: 99%

Fourier Transform Infrared Spectroscopy of Skin Cancer Cells and Tissues

Mostaço-Guidolin

Murakami

Nomizo

et al. 2009

Applied Spectroscopy Reviews

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The aim of this review is to combine all the information related to the characterization of skin tissues and cells, focusing on the identification of the specific biochemical characteristics of skin cancer. We have characterized two types of melanoma by FTIR spectroscopy: a murine melanoma (B16F10 cell line) and a human melanoma (C8161 cell line). The cells were deposited on IR transparent CaF 2 windows, the spectral range used lay between 900-4000 cm −1 , transmission mode with 2 cm −1 resolution, and 32 scans. A biochemical association is presented for all the absorption bands identified in this study. Besides the characterization of both cell lines above, a collection of works done in the area of skin cancer was also carried out, in this review; some interesting results obtained by different authors with respect to the characterization of different samples (melanomas, follicle sheath, basal cell carcinoma, epidermis tissues, dermis tissue, and human stratum corneum) are presented and compared to the chemical and biological associations performed in each case. The identification of biochemical injuries provides important information that, associated with clinical examination, can assist the diagnosis of diseases. Several FTIR techniques can be used in the diagnosis of biochemical changes in biological tissues, by identifying molecular markers associated with malignant and benign changes or variations in the composition of amino acids in tissues and cells. In the near future, a further study to compare histopatological analysis and biochemical characterization by FTIR spectroscopy would be interesting, in order

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“…Black or brown dots may appear after acute ultraviolet exposure; however, these dots tend to disappear over time (Dobrosavljevic et al, 2009;Tronnier et al, 2000;Hofmann-Wellenhof et al, 1998;Hofmann-Wellenhof et al, 1997). It is interesting to note that many nonultraviolet-induced dots that are successfully tape stripped off the skin reappear with time.…”

Section: Dotsmentioning

confidence: 94%