Changes in colonization of residents and staff of a long-term care facility and an adjacent acute-care hospital geriatric unit by multidrug-resistant bacteria over a four-year period

Abstract

A significant decrease in the proportions of staff and residents of an LTCF colonized by MDR bacteria was observed over a 4-y interval.

Analysis of multidrug-resistant bacteria in 3223 patients with hospital-acquired infections (HAI) from a tertiary general hospital in China

“…In our study, patients aged above 60 years represented the highest proportion of patients with MDR bacterial infections, followed by middle-aged patients (40-59 years), and infants (<2 years). Elderly patients are generally consider to be at high risk of nosocomial infections, due to a higher disease prevalence in this population, including neurological disorders, diabetes and cardiovascular diseases [21][22][23][24][25].…”

Bloodstream infections in older patients

“…56 March et al found that among LTCF residents in 2012, 54% were colonized with 1 resistant organism. 57 Contributing factors to high rates of colonization and infection of elderly with MDROs include substantial antimicrobial exposure, frequent hospitalizations, indwelling devices, dementia and low functional status, and as a result -high rates of cross transmission in these settings. 6,58 Dekinger et al demonstrated that among patients aged 65 and older admitted to hospital, rates of MDROs are approximately 2-fold higher for MRSA and vancomycin resistant enterococci (VRE) and 3-fold higher for multidrug resistant (MDR) Gram negative compared to younger patients.…”

Impact of hand hygiene on the infectious risk in nursing home residents: A systematic review

“…Among the 46 remaining studies, 33 investigated multifaceted interventions which covered other aspects of infection control besides HH, 39,43,46,50,52,53,56,59,61,63,65 whereas 13 described interventions based on HH only. 10,45,[47][48][49]51,54,55,57,58,60,62,64 The interventions on HH were diverse and included educational programs for the staff and the residents (in 57% of the 46 studies describing interventions), 10,14,20,21,23,27,29,39,43,45,47,48,50,51,53,55-65 implementation of new guidelines (28% of studies), [10][11][12][13]15,17,19,20,22,26,…”

“…); however, some studies also considered the infectious risk among staff.The most frequently reported outcome was the rate of colonization with or infection caused by S aureus, especially methicillin-54%) were focused on bacterial infections and colonization with bacteria, including (besides S aureus) vancomycin-resistant enterococci,13,22,25,40,[55][56][57] Clostridium difficile, 10 group A streptococci,14,23,30 or resistant Enterobacteriaceae, such as Escherichia coli or Klebsiella pneumoniae 34,40,[42][43][44]49,56,57. Gastroenteritis (mostly caused by norovirus) was the reported outcome in 12 studies (21%),12,15,16,18,21,26,28,31,36,38,41,46 and respiratory infections or…”