Changes in cognitive function after a 12-week exercise intervention in adults with Down syndrome

Ptomey, Lauren T.; Szabo, Amanda N.; Willis, Erik A.; Gorczyca, Anna M.; Greene, Jerry L.; Danón, J; Donnelly, Joseph E.

doi:10.1016/j.dhjo.2018.02.003

Cited by 55 publications

(76 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Strengths of the current study included the excellent adherence rate as well as the homogeneous and large sample size. Conversely, many studies that have been focused on the influence of regular exercise on people with ID have recruited mixed (male and female) groups in order to increase sample size with the aim of strengthening research design [ 6 , 37 ]. In addition, some studies have recruited participants with intellectual disability matched for intelligence quotient but having different diagnoses [ 38 ].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

A Short-Term Resistance Training Circuit Improved Antioxidants in Sedentary Adults with Down Syndrome

Rosety-Rodriguez

Bernardi²,

Elosegui

et al. 2021

Oxidative Medicine and Cellular Longevity

View full text Add to dashboard Cite

Previous studies have found aerobic training improved oxidative damage in people with Down syndrome (DS). However, there is a lack of information regarding the influence of resistance training on redox imbalance in this population. Accordingly, this study was conducted to determine the effect of resistance training (RT) on antioxidant defence system in sedentary adults with DS. Thirty-six male adults with DS were recruited through different community support groups. Eighteen were randomly assigned to perform a circuit RT program with 6 stations, 3 days/week for 12 weeks. Plasma total antioxidant status (TAS), reduced glutathione (GHS), ascorbate, serum α-tocopherol, and erythrocyte glutathione reductase activity were assessed. Plasma malondialdehyde (MDA) and carbonyl groups (CG) were assessed as markers of oxidative damage. Muscle strength was also measured. Dynamic torque of knee extensors and flexors as well as maximal handgrip strength was significantly improved after the completion of the training program. Plasma levels of TAS and erythrocyte glutathione reductase (GR) activity were significantly increased. Conversely, MDA and CG levels were significantly reduced. It was concluded RT improved antioxidant defence system and reduced oxidative damage in adults with DS. Further, long-term studies are required to determine whether the increased antioxidant system may improve clinical outcomes of adults with DS.

show abstract

Section: Discussionmentioning

confidence: 99%

“…In a recent study, Oppewal et al [ 5 ] reported that physical fitness has been independently associated with survival in adults with intellectual disability (ID). In addition, increased exercise may have positive changes on memory and other cognitive functions [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

A Short-Term Resistance Training Circuit Improved Antioxidants in Sedentary Adults with Down Syndrome

Rosety-Rodriguez

Bernardi²,

Elosegui

et al. 2021

Oxidative Medicine and Cellular Longevity

View full text Add to dashboard Cite

show abstract

“…), as well as other outcomes. For instance, recent evidence suggests that video conferencing might improve moderate-to vigorous physical activity (Ptomey, Szabo, Willis, Greene, et al, 2018) and cognitive variables (Ptomey, Szabo, Willis, Gorczyca, et al, 2018).…”

Section: Discussionmentioning

confidence: 99%

“…It is estimated that there are approximately 250,000 people with Down syndrome in Mexico (Romero et al, 2014), a similar estimation to the 250,000 to 400,000 diagnosed in the United States (Ptomey, Szabo, Willis, Gorczyca, et al, 2018). The life expectancy for this group is approximately of 55 years, given to physical and congenital heart problems.…”

Section: Introductionmentioning

confidence: 94%

Untitled

2019

JPES

View full text Add to dashboard Cite

Purpose: Was to determine the effect of a physical fitness program on body composition and isometric strength in children with Down syndrome. Methods: Twenty-two children with DS, 13 in the experimental group (EG) and 9 in the control group (CG). Isometric handgrip strength, body height, weight, triceps and the medial calf skinfolds were measured. The body mass index (BMI) was computed from body height and weight. The physical fitness program was performed for 16-weeks, 5 times per week, on 55-min sessions. Results: Significant pre-to post-intervention reductions in BMI were observed in both EG (22.2 ± 2.5 vs. 20.7 ± 2.5 kg/m 2 ; P ≤ 0.0001), and CG (23.3 ± 4.9 vs. 21.9 ± 4.6 kg/m2; P ≤ 0.001). Significant pre-to post-intervention reductions were observed in medial calf skinfold and isometric strength in the EG (14.9 ± 5.5 vs. 14.6 ± 3.2 mm; P = 0.008) and (2.4 ± 4.0 vs. 9.2 ± 2.0 kg; P ≤ 0.0001), respectably. Conclusion: A physical fitness program improved isometric strength and body composition in Down syndrome participants. Children with Down syndrome can improve their quality of life by performing structured physical fitness training.

show abstract

“…The practise of physical activity would therefore improve the quality of life of people with DS. Furthermore, some studies show that physical exercise also increases some cognitive capacities, such as memory [12]. Lastly, as they are dependent people, the improvement of their autonomy positively impacts on the quality of life of the people around them [13].…”

Section: Introductionmentioning

confidence: 99%

Feasibility and Reliability of a Physical Fitness Test Battery in Individuals with Down Syndrome

Ruiz

Alcántara-Cordero

Ruiz-Gavilán

et al. 2019

IJERPH

View full text Add to dashboard Cite

Background: Down syndrome (DS) is a genetic disorder that occurs because of an abnormal division between cells that results in an extra copy of chromosome 21. Some studies show that physical exercise in people with DS increases some cognitive capacities, such as memory, and improves the quality of life. Aim: The main aim of this study was to perform an analysis of the reliability and feasibility of the SAMU-Disability Fitness (DISFIT) battery in adults with DS. Methods: A cross-sectional study with a test–retest design was performed in a maximum interval of 2 weeks in 37 subjects (11 women and 26 men) aged between 21 and 58 years old with DS. Eight field-based fitness tests were proposed to assess the physical fitness (PF) of adults with DS: Body Mass Index (BMI), Waist Circumference (WC), the Timed Up and Go test (TUG), the Deep Trunk Flexibility test (DTF), the Hand Grip test (HG), the Timed Stand Test (TST), the 30-s Sit-Up (SUP) and the 6-Min Walk Test (6MWT). Results: The intra-class correlation coefficient (ICC) in all the tests was good and high (>0.80), except for the 6MWT, whose reliability was fair. Conclusion: The SAMU-DISFIT battery is a reliable and feasible physical fitness battery which has been created with the purpose of establishing tests which measure the four basic components of PF (flexibility, cardiorespiratory fitness, musculoskeletal fitness and motor fitness) in adults with DS.

show abstract

Changes in cognitive function after a 12-week exercise intervention in adults with Down syndrome

Abstract: Increased exercise may have positive changes on memory and other cognitive functions.

Cited by 55 publications

References 29 publications

A Short-Term Resistance Training Circuit Improved Antioxidants in Sedentary Adults with Down Syndrome

A Short-Term Resistance Training Circuit Improved Antioxidants in Sedentary Adults with Down Syndrome

Untitled

Feasibility and Reliability of a Physical Fitness Test Battery in Individuals with Down Syndrome

Contact Info

Product

Resources

About